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Troponin I, cardiac muscle (Tnni3) Recombinant Protein | Tnni3 recombinant protein
Recombinant Mouse Troponin I, cardiac muscle (Tnni3)
Gene Names
Tnni3; Tn1; cTnI
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Troponin I; cardiac muscle (Tnni3); Recombinant Mouse Troponin I; cardiac muscle; Cardiac troponin I; Tnni3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-211. Full Length of Mature Protein
Sequence
ADESSDAAGEPQPAPAPVRRRSSANYRAYATEPHAKKKSKISASRKLQLKTLMLQIAKQEMEREAEERRGEKGRVLRTRCQPLELDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLDLRAHLKQVKKEDIEKENREVGDWRKNIDALSGMEGRKKKFEG
Species
Mus musculus (Mouse)
Production Note
Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to [email protected] for more details.
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
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Related Product Information for Tnni3 recombinant protein
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Product Categories/Family for Tnni3 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40.1 kDa
NCBI Official Full Name
troponin I, cardiac muscle
NCBI Official Synonym Full Names
troponin I, cardiac 3
NCBI Official Symbol
Tnni3
NCBI Official Synonym Symbols
Tn1; cTnI
NCBI Protein Information
troponin I, cardiac muscle; cardiac troponin I
UniProt Protein Name
Troponin I, cardiac muscle
Protein Family
UniProt Gene Name
Tnni3
UniProt Entry Name
TNNI3_MOUSE
Uniprot Description
TNNI3: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. Binds to actin and tropomyosin. Interacts with TRIM63. Interacts with STK4/MST1. Belongs to the troponin I family.
Protein type: Motility/polarity/chemotaxis; Actin-binding; Motor
Cellular Component: sarcomere; troponin complex; myofibril; contractile fiber; cell; cytoplasm
Molecular Function: troponin T binding; troponin C binding; protein domain specific binding; metal ion binding; calcium channel inhibitor activity; actin binding; protein kinase binding; calcium-dependent protein binding
Biological Process: regulation of smooth muscle contraction; cellular calcium ion homeostasis; striated muscle contraction; heart contraction; regulation of muscle contraction; heart development; regulation of systemic arterial blood pressure by ischemic conditions; ventricular cardiac muscle morphogenesis; vasculogenesis; negative regulation of ATPase activity; cardiac muscle contraction
Research Articles on Tnni3
1. R193H and R205H mutation increase the binding affinity of Troponin I for Troponin T and Troponin C.
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Product Notes
The Tnni3 tnni3 (Catalog #AAA1173692) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-211. Full Length of Mature Protein. The amino acid sequence is listed below: ADESSDAAGE PQPAPAPVRR RSSANYRAYA TEPHAKKKSK ISASRKLQLK TLMLQIAKQE MEREAEERRG EKGRVLRTRC QPLELDGLGF EELQDLCRQL HARVDKVDEE RYDVEAKVTK NITEIADLTQ KIYDLRGKFK RPTLRRVRIS ADAMMQALLG TRAKESLDLR AHLKQVKKED IEKENREVGD WRKNIDALSG MEGRKKKFEG . It is sometimes possible for the material contained within the vial of "Troponin I, cardiac muscle (Tnni3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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