Mouse Cardiac Troponin I Monoclonal Antibody | anti-CTNI antibody

Anti-Cardiac Troponin I Mouse mAb

Cat. Num. AAA477386

• Gene Names: TNNI3; CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: Affinity Purified
• Synonyms: Cardiac Troponin I; Monoclonal Antibody; Anti-Cardiac Troponin I Mouse mAb; cardiac muscle; Cardiac troponin I; cardiomyopathy; dilated 2A (autosomal recessive); Cardiomyopathy; familial hypertrophic; 7; included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; Tn1; Tni; TNN I3; TNNC 1; TNNC1; TNNI3; TNNI3_HUMAN; Troponin I; Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I; cardiac 3; TroponinI; Ttroponin I type 3 (cardiac); anti-CTNI antibody

• Host: Mouse
• Reactivity: Human, Mouse, Rat
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone Number: 5C6-B6
• Specificity: This antibody detects endogenous levels of Cardiac Troponin I.
• Purity/Purification: Affinity Purified
• Form/Format: PBS(pH 7.4) containing with 0.03% Proclin300.
• Sequence Length: 210

• Applicable Applications for anti-CTNI antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA: 1:10000; WB: 1:1000
• Immunogen: Synthetic peptides corresponding to the sequence of human Cardiac Troponin I.
• Preparation and Storage: Store at 4 degree C for short term.; Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of extracts from Rat and mouse heart tissue using Troponin I (MBS477386, dilution 1:1000) Mouse mAb.Predicted band size:28kDa.Observed band size:28kDa.)

Related Product Information for anti-CTNI antibody

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

NCBI and Uniprot Product Information

• NCBI GI #: 151101270
• NCBI GeneID: 7137
• NCBI Accession #: NP_000354.4
• NCBI GenBank Nucleotide #: NM_000363.4
• UniProt Accession #: P19429
• Molecular Weight: 28kDa
• NCBI Official Full Name: troponin I, cardiac muscle
• NCBI Official Synonym Full Names: troponin I3, cardiac type
• NCBI Official Symbol: TNNI3
• NCBI Official Synonym Symbols: CMH7; RCM1; cTnI; CMD2A; TNNC1; CMD1FF
• NCBI Protein Information: troponin I, cardiac muscle
• UniProt Protein Name: Troponin I, cardiac muscle
• UniProt Gene Name: TNNI3
• UniProt Synonym Gene Names: TNNC1

NCBI Description

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]

Uniprot Description

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.