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SDS-Page (3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)

HVEM/TNFRSF14 recombinant protein

Recombinant HVEM/TNFRSF14

Applications
SDS-Page
Purity
> 90% by SDS - PAGE
Synonyms
HVEM/TNFRSF14; Recombinant HVEM/TNFRSF14; Tnfrsf14; Herpes virus entry mediator A; Herpesvirus entry mediator A; HveA; Tumor necrosis factor receptor-like 2; TR2; CD270; Hvem; Atar; Tumor necrosis factor receptor superfamily member 14; HVEM/TNFRSF14 recombinant protein
Ordering
For Research Use Only!
Host
Baculovirus
Purity/Purification
> 90% by SDS - PAGE
Form/Format
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Concentration
0.25mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence Positions
39-206aa
Sequence
QPSCRQEEFL VGDECCPMCN PGYHVKQVCS EHTGTVCAPC PPQTYTAHAN GLSKCLPCGV CDPDMGLLTW QECSSWKDTV CRCIPGYFCE NQDGSHCSTC LQHTTCPPGQ RVEKRGTHDQ DTVCADCLTG TFSLGGTQEE CLPWTNCSAF QQEVRRGTNS TDTTCSSQ
Sequence Length
275
Applicable Applications for HVEM/TNFRSF14 recombinant protein
SDS-PAGE
Tag
hIgG-His-Tag
Predicted nterm
Gln 39
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Preparation and Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

SDS-Page

(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)

SDS-Page (3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Related Product Information for HVEM/TNFRSF14 recombinant protein
HVEM/TNFRSF14, also known as tumor necrosis factor receptor superfamily member 14, is a member of TNF receptor superfamily. This protein was originally known as herpesvirus entry mediator A (HveA); HveB and HveC are structurally unrelated proteins of the immunoglobulin superfamily. The cytoplasmic region of this receptor was found to bind to several TNF receptor associated factor (TRAF) family members, which may mediate the signal transduction pathways that activate the immune response. It promotes and inhibits T cell activity. This protein signals via the TRAF2-TRAF3 E3 ligase pathway to promote immune cell survival and differentiation. It participates in cell to cell contact signaling between antigen presenting cells and lymphocytes. This protein downregulates CD28 costimulatory signaling, restricting memory and alloantigen-specific immune response. Recombinant mouse HVEM/TNFRSF14, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for HVEM/TNFRSF14 recombinant protein
References
Choi EK., et al. (2013) J Endocrinol. 220:25-33.;; Kotsiou E., et al. (2018) Blood. 128:72-81.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
45.3kDa (407aa)
NCBI Official Full Name
Tumor necrosis factor receptor superfamily member 14
UniProt Protein Name
Protein Tnfrsf14
UniProt Gene Name
Tnfrsf14
UniProt Entry Name
Q80WM9_MOUSE

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Product Notes

The HVEM/TNFRSF14 tnfrsf14 (Catalog #AAA201181) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 39-206aa. AAA Biotech's HVEM/TNFRSF14 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the HVEM/TNFRSF14 tnfrsf14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: QPSCRQEEFL VGDECCPMCN PGYHVKQVCS EHTGTVCAPC PPQTYTAHAN GLSKCLPCGV CDPDMGLLTW QECSSWKDTV CRCIPGYFCE NQDGSHCSTC LQHTTCPPGQ RVEKRGTHDQ DTVCADCLTG TFSLGGTQEE CLPWTNCSAF QQEVRRGTNS TDTTCSSQ . It is sometimes possible for the material contained within the vial of "HVEM/TNFRSF14, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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