BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (Tnfaip1) Recombinant Protein | Tnfaip1 recombinant protein
Recombinant Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (Tnfaip1)
Gene Names
Tnfaip1; Edp1; Edp-1; Tnfip1; Bacurd2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (Tnfaip1); Recombinant Mouse BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (Tnfaip1); Tnfaip1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-316, Full length protein
Sequence
MSGDTCLCPASGAKPKISGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQSRQEIQELMAEAKYYLIQGLVSTCQTALQDKKDSYQPVCNIPIITSLREEDRLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASPSEDEDTFELRDRVRRIHVKRYSTYDDRQLGHQSTHRD
Sequence Length
316
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Tnfaip1 recombinant protein
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,134 Da
NCBI Official Full Name
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
NCBI Official Synonym Full Names
tumor necrosis factor, alpha-induced protein 1 (endothelial)
NCBI Official Symbol
Tnfaip1
NCBI Official Synonym Symbols
Edp1; Edp-1; Tnfip1; Bacurd2
NCBI Protein Information
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
UniProt Protein Name
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
UniProt Gene Name
Tnfaip1
UniProt Synonym Gene Names
Edp1
Uniprot Description
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity ().
Research Articles on Tnfaip1
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Product Notes
The Tnfaip1 tnfaip1 (Catalog #AAA1195044) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-316, Full length protein. The amino acid sequence is listed below: MSGDTCLCPA SGAKPKISGF KGGGLGNKYV QLNVGGSLYY TTVRALTRHD TMLKAMFSGR MEVLTDKEGW ILIDRCGKHF GTILNYLRDD TITLPQSRQE IQELMAEAKY YLIQGLVSTC QTALQDKKDS YQPVCNIPII TSLREEDRLI ESSTKPVVKL LYNRSNNKYS YTSNSDDHLL KNIELFDKLS LRFNGRVLFI KDVIGDEICC WSFYGQGRKL AEVCCTSIVY ATEKKQTKVE FPEARIYEET LNVLLYETPR VPDNSLLEAT SRSRSQASPS EDEDTFELRD RVRRIHVKRY STYDDRQLGH QSTHRD. It is sometimes possible for the material contained within the vial of "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (Tnfaip1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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