STING recombinant protein
Recombinant Human STING Protein
Gene Names
TMEM173; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; STING-beta
Reactivity
Human
Applications
ELISA, Western Blot, SDS-Page
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
STING; Recombinant Human STING Protein; ERIS; MITA; Stimulator of interferon genes protein; hSTING; Endoplasmic reticulum interferon stimulator; Mediator of IRF3 activation; hMITA; Transmembrane protein 173; STING recombinant protein
Host
E Coli
Reactivity
Human
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Liquid in a 0.2 μm filtered solution of PBS, pH7.4.
Sequence
MGHHHHHHGS LQDSEVNQEA KPEVKPEVKP ETHINLKVSD GSSEIFFKIK KTTPLRRLME AFAKRQGKEM DSLRFLYDGI RIQADQAPED LDMEDNDIIE AHREQIGGVA HGLAWSYYIG YLRLILPELQ ARIRTYNQHY NNLLRGAVSQ RLYILLPLDC GVPDNLSMAD PNIRFLDKLP QQTGDHAGIK DRVYSNSIYE LLENGQRAGT CVLEYATPLQ TLFAMSQYSQ AGFSREDRLE QAKLFCRTLE DILADAPESQ NNCRLIAYQE PADDSSFSLS QEVLRHLRQE EKEEV
Sequence Length
379
Applicable Applications for STING recombinant protein
ELISA (EIA), Western Blot (WB), SDS-PAGE (SDS), Mass Spectometry (MS)
Endotoxin
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Directions for Use
Please minimize freeze/thaw cycles.
Preparation and Storage
Store it at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Related Product Information for STING recombinant protein
Recombinant Human STING Protein is produced by E Coli expression system and the target gene encoding Val155-Val341 is expressed with a 6His, Sumo tag at the N-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
stimulator of interferon genes protein isoform 1
NCBI Official Synonym Full Names
transmembrane protein 173
NCBI Official Symbol
TMEM173
NCBI Official Synonym Symbols
ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; STING-beta
NCBI Protein Information
stimulator of interferon genes protein
UniProt Protein Name
Stimulator of interferon genes protein
UniProt Gene Name
TMEM173
UniProt Synonym Gene Names
ERIS; MITA; STING; hSTING; ERIS; hMITA
UniProt Entry Name
STING_HUMAN
NCBI Description
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Research Articles on STING
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Product Notes
The STING tmem173 (Catalog #AAA8305104) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Human STING Protein reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STING can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), SDS-PAGE (SDS), Mass Spectometry (MS). Researchers should empirically determine the suitability of the STING tmem173 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGHHHHHHGS LQDSEVNQEA KPEVKPEVKP ETHINLKVSD GSSEIFFKIK KTTPLRRLME AFAKRQGKEM DSLRFLYDGI RIQADQAPED LDMEDNDIIE AHREQIGGVA HGLAWSYYIG YLRLILPELQ ARIRTYNQHY NNLLRGAVSQ RLYILLPLDC GVPDNLSMAD PNIRFLDKLP QQTGDHAGIK DRVYSNSIYE LLENGQRAGT CVLEYATPLQ TLFAMSQYSQ AGFSREDRLE QAKLFCRTLE DILADAPESQ NNCRLIAYQE PADDSSFSLS QEVLRHLRQE EKEEV. It is sometimes possible for the material contained within the vial of "STING, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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