Mouse transmembrane channel-like 1 ELISA Kit | TMC1 elisa kit
Mouse Transmembrane channel-like protein 1, TMC1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TMC1: Required for the normal function of cochlear hair cells. Defects in TMC1 are the cause of deafness autosomal dominant type 36 (DFNA36). DFNA36 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNA36 is a bilateral hearing loss, and begins at 5-10 years of age. It progresses to profound deafness within 10-15 years. Defects in TMC1 are the cause of deafness autosomal recessive type 7 (DFNB7); also known as autosomal recessive neurosensory deafness type 11 (DFNB11). This hearing loss is congenital and profound. Belongs to the TMC family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: membrane; integral to membrane; stereocilium bundle tip; external side of plasma membrane
Molecular Function: voltage-gated calcium channel activity
Biological Process: sensory perception of sound; vestibular reflex; transport; auditory receptor cell development; ion transport; detection of mechanical stimulus involved in sensory perception of sound
Disease: Deafness, Autosomal Recessive 7
Research Articles on TMC1
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Product Notes
The Mouse TMC1 tmc1 (Catalog #AAA9325717) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9325717 ELISA Kit recognizes Mouse TMC1. It is sometimes possible for the material contained within the vial of "transmembrane channel-like 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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