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Typical Testing Data/Standard Curve (for reference only)

Goat T lymphocyte subpopulation CD3/4/8 ELISA Kit | TLS elisa kit

Goat T lymphocyte subpopulation CD3/4/8 ELISA Kit

Gene Names
FUS; TLS; ALS6; FUS1; POMP75; HNRNPP2
Reactivity
Goat
Synonyms
T lymphocyte subpopulation CD3/4/8; Goat T lymphocyte subpopulation CD3/4/8 ELISA Kit; TLS elisa kit
Ordering
For Research Use Only!
Reactivity
Goat
Preparation and Storage
Store all reagents at 2-8 degree C

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Product Categories/Family for TLS elisa kit

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
53,426 Da
NCBI Official Full Name
TLS
NCBI Official Synonym Full Names
fused in sarcoma
NCBI Official Symbol
FUS
NCBI Official Synonym Symbols
TLS; ALS6; FUS1; POMP75; HNRNPP2
NCBI Protein Information
RNA-binding protein FUS; oncogene FUS; oncogene TLS; fus-like protein; 75 kDa DNA-pairing protein; fusion gene in myxoid liposarcoma; translocated in liposarcoma protein; heterogeneous nuclear ribonucleoprotein P2
UniProt Protein Name
RNA-binding protein FUS
UniProt Gene Name
FUS
UniProt Synonym Gene Names
TLS
UniProt Entry Name
FUS_HUMAN

NCBI Description

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]

Uniprot Description

hnRNP P2: Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity. Component of nuclear riboprotein complexes. Interacts with ILF3, TDRD3 and SF1. Interacts through its C-terminus with SFRS13A. Interacts with OTUB1 and SARNP. Ubiquitous. Belongs to the RRM TET family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Nuclear receptor co-regulator; DNA-binding; RNA splicing; Oncoprotein

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: identical protein binding; protein binding; DNA binding; zinc ion binding; RNA binding; nucleotide binding

Biological Process: nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression

Disease: Amyotrophic Lateral Sclerosis 6, With Or Without Frontotemporal Dementia; Tremor, Hereditary Essential, 4

Research Articles on TLS

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Product Notes

The Goat TLS fus (Catalog #AAA741631) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA741631 ELISA Kit recognizes Goat TLS. It is sometimes possible for the material contained within the vial of "T lymphocyte subpopulation CD3/4/8, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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