Mouse toll-like receptor adaptor molecule 2 ELISA Kit | TICAM2 elisa kit
Mouse TIR domain-containing adapter molecule 2, TICAM2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TICAM2: a toll-like receptor adapter that participates in induction of type 1 interferons. Transiently phosphorylated on serine-16 during LPS/Toll-like receptor 4 (TLR4) signaling. Activated TLR4 associates with four adapter proteins, MyD88, TIRAP, TICAM-1 (Trif), and TICAM-2.
Protein type: Adaptor/scaffold
Cellular Component: Golgi apparatus; interleukin-1 receptor complex; membrane; endoplasmic reticulum; late endosome; early endosome; cytoplasm; plasma membrane; endosome
Molecular Function: protein binding; signal transducer activity; interleukin-1 receptor binding; protein heterodimerization activity; phospholipid binding
Biological Process: positive regulation of interferon-gamma production; positive regulation of I-kappaB kinase/NF-kappaB cascade; immune system process; negative regulation of toll-like receptor 4 signaling pathway; positive regulation of toll-like receptor 4 signaling pathway; positive regulation of interleukin-6 production; innate immune response; inflammatory response; signal transduction; regulation of interferon-beta biosynthetic process; regulation of I-kappaB kinase/NF-kappaB cascade; regulation of cytokine production
Research Articles on TICAM2
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Product Notes
The Mouse TICAM2 ticam2 (Catalog #AAA9342084) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9342084 ELISA Kit recognizes Mouse TICAM2. It is sometimes possible for the material contained within the vial of "toll-like receptor adaptor molecule 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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