Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Transforming Growth Factor beta-2/TGFbeta2/TGFB2 Recombinant Protein | TGFbeta2/TGFB2 recombinant protein

Recombinant Mouse Transforming Growth Factor beta-2/TGFbeta2/TGFB2 Protein

Gene Names
Tgfb2; Tgfb-2; BB105277; Tgf-beta2
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Transforming Growth Factor beta-2/TGFbeta2/TGFB2; Recombinant Mouse Transforming Growth Factor beta-2/TGFbeta2/TGFB2 Protein; TGFB2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; MGC116892; Polyergin; TGF-beta2; TGF-beta-2; transforming growth factor beta-2; TGFbeta2/TGFB2 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 4 mM HCl.
Sequence Positions
Ala303-Ser414
Sequence Length
414
Species
Mouse
Endotoxin
<1.0 EU per mug as determined by LAL test.
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for TGFbeta2/TGFB2 recombinant protein
Transforming growth factor beta 2 (TGF-beta2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-beta2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-beta isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-beta receptor type II (TbetaR-II), and a TGF-beta receptor type I (TbetaR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-beta expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 12.7 kDa
Actual Protein Molecular Mass: 25-28 kDa
NCBI Official Full Name
transforming growth factor beta-2 isoform 1 preproprotein
NCBI Official Synonym Full Names
transforming growth factor, beta 2
NCBI Official Symbol
Tgfb2
NCBI Official Synonym Symbols
Tgfb-2; BB105277; Tgf-beta2
NCBI Protein Information
transforming growth factor beta-2
UniProt Protein Name
Transforming growth factor beta-2 proprotein
UniProt Gene Name
Tgfb2
UniProt Synonym Gene Names
LAP; TGF-beta-2

NCBI Description

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Mice lacking a functional copy of this gene display developmental defects in multiple organs and perinatal lethality. Heterozygous mutant mice exhibit aortic root aneurysm. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]

Uniprot Description

Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.

Research Articles on TGFbeta2/TGFB2

Similar Products

Product Notes

The TGFbeta2/TGFB2 tgfb2 (Catalog #AAA2553636) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Ala303-Ser414. It is sometimes possible for the material contained within the vial of "Transforming Growth Factor beta-2/TGFbeta2/TGFB2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.