Tissue factor pathway inhibitor ELISA Kit | TFPI elisa kit

Mouse TFPI PicoKine ELISA Kit

Cat. Num. AAA177538

• Gene Names: Tfpi; EPI; LACI; AW552122; A630013F22Rik
• Reactivity: Mouse. There is no detectable cross-reactivity with other relevant proteins.
• Synonyms: Tissue factor pathway inhibitor; Mouse TFPI PicoKine ELISA Kit; Anti convertin; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein associated coagulation inhibitor; Lipoprotein-associated coagulation inhibitor; TFI; TFPI 1; TFPI; TFPI1; TFPI1_HUMAN; Tissue factor pathway inhibitor (lipoprotein associated coagulation inhibitor); tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); TFPI elisa kit

• Reactivity: Mouse. There is no detectable cross-reactivity with other relevant proteins.
• Sequence Length: 306

• Samples: Cell culture supernates, serum and plasma (heparin, EDTA)
• Assay Type: Sandwich
• Sensitivity: <10pg/ml
• Immunogen: NSO, L29-N306
• Intra-Assay Precision: Sample 1: n=16; Mean(ng/ml): 1.05; Standard deviation: 0.048; CV(%): 4.6 Sample 2: n=16; Mean(ng/ml): 2.91; Standard deviation: 0.122; CV(%): 4.2 Sample 3: n=16; Mean(ng/ml): 5.34; Standard deviation: 0.203; CV(%): 3.8
• Inter-Assay Precision: Sample 1: n=24; Mean(ng/ml): 1.21; Standard deviation: 0.076; CV(%): 6.3 Sample 2: n=24; Mean(ng/ml): 3.45; Standard deviation: 0.193; CV(%): 5.6 Sample 3: n=24; Mean(ng/ml): 5.82; Standard deviation: 0.285; CV(%): 4.9
• Assay Range: 156pg/ml-10,000pg/ml
• Preparation and Storage: Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

Typical Testing Data/Standard Curve (for reference only)

(Mouse TFPI PicoKine ELISA Kit standard curve )

Related Product Information for TFPI elisa kit

Description: Sandwich ELISA kit of Quantitative Detection for Mouse TFPI
Background: TFPI(Tissue factor pathway inhibitor),also known as EPI, LACI or TFPI1, is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). The gene for TFPI is located on chromosome 2q31-q32.1, and has nine exons which span 70 kb. TFPI consists of a highly negatively-charged amino-terminus, three tandemly-linked Kunitz domains, and a highly positively-charged carboxy-terminus. TFPI contributes significantly to the inhibition of Xa in vivo, despite being present at concentrations of only 2.5 nM.

NCBI and Uniprot Product Information

• NCBI GI #: 33859644
• NCBI GeneID: 21788
• NCBI Accession #: NP_035706.1
• NCBI GenBank Nucleotide #: NM_011576.1
• UniProt Accession #: O54819; Q9Z2U8
• Molecular Weight: 28,949 Da
• NCBI Official Full Name: tissue factor pathway inhibitor isoform a
• NCBI Official Synonym Full Names: tissue factor pathway inhibitor
• NCBI Official Symbol: Tfpi
• NCBI Official Synonym Symbols: EPI; LACI; AW552122; A630013F22Rik
• NCBI Protein Information: tissue factor pathway inhibitor; extrinsic pathway inhibitor; lipoprotein-associated coagulation inhibitor
• UniProt Protein Name: Tissue factor pathway inhibitor
• Protein Family: Tissue factor pathway inhibitor
• UniProt Gene Name: Tfpi
• UniProt Synonym Gene Names: TFPI; EPI; LACI
• UniProt Entry Name: TFPI1_MOUSE

Uniprot Description

TFPI: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Secreted; Inhibitor; Secreted, signal peptide

Cellular Component: extracellular space; cell surface; extracellular region

Molecular Function: serine-type endopeptidase inhibitor activity; protease inhibitor activity

Biological Process: hemostasis; negative regulation of peptidase activity; blood coagulation