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Testing Data

anti-Human Transferrin Antibody | anti-TF antibody

Transferrin Antibody

Gene Names
TTR; CTS; ATTR; CTS1; PALB; TBPA; HEL111; HsT2651
Reactivity
Human
Applications
Western Blot
Synonyms
Transferrin; Transferrin Antibody; anti-TF antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to residues 125-160 of human Prealbumin PA.
Form/Format
In 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol.
Sequence Length
147
Applicable Applications for anti-TF antibody
Western Blot (WB)
Application Notes
WB: 1:5,000
Preservative
0.05% Sodium Azide.
Cellular Localization
Secretory Protein
Positive Control
Human plasma
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.

Testing Data

Testing Data
Related Product Information for anti-TF antibody
Transthyretin (TTR) originally called prealbumin is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol. Prealbumin concentrations are disproportionately high in human ventricular cerebrospinal fluid (CSF). Over 80 different disease-causing mutations in prealbumin have been reported. TTR is known to be associated with the amyloid diseases senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC).
References
Mita S., Maeda S., Shimada K., Araki S.; "Cloning and sequence analysis of cDNA for human prealbumin."; Biochem. Biophys. Res. Commun. 124:558-564(1984). Sasaki H., Yoshioka N., Takagi Y., Sakaki Y.; "Structure of the chromosomal gene for human serum prealbumin."; Gene 37:191-197(1985). Bergstroem J., Patrosso M.C., Colussi G., Salvadore M., Penco S., Lando G., Marocchi A., Ueda A., Nakamura M., Ando Y.; "A novel type of familial transthyretin amyloidosis, ATTR Asn124Ser, with co-localization of kappa light chains."; Amyloid 14:141-145(2007).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16kDa
NCBI Official Full Name
transthyretin
NCBI Official Synonym Full Names
transthyretin
NCBI Official Symbol
TTR
NCBI Official Synonym Symbols
CTS; ATTR; CTS1; PALB; TBPA; HEL111; HsT2651
NCBI Protein Information
transthyretin
UniProt Protein Name
Transthyretin
Protein Family
UniProt Gene Name
TTR
UniProt Synonym Gene Names
PALB

NCBI Description

This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier protein, which transports thyroid hormones in the plasma and cerebrospinal fluid. It is also involved in the transport of retinol (vitamin A) in the plasma by associating with retinol-binding protein. The protein may also be involved in other intracellular processes including proteolysis, nerve regeneration, autophagy and glucose homeostasis. Mutations in this gene are associated with amyloid deposition, predominantly affecting peripheral nerves or the heart, while a small percentage of the gene mutations are non-amyloidogenic. The mutations are implicated in the etiology of several diseases, including amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis and carpal tunnel syndrome. [provided by RefSeq, Aug 2017]

Uniprot Description

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

Research Articles on TF

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Product Notes

The TF ttr (Catalog #AAA850284) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Transferrin Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Transferrin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:5,000. Researchers should empirically determine the suitability of the TF ttr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Transferrin, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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