Mouse transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) ELISA Kit | TCF3 elisa kit
Mouse Transcription factor E2-alpha, TCF3 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
E2A: a transcription factor that plays major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Heterodimers between E2A and tissue-specific basic helix-loop-helix (bHLH) Dimers bind DNA on E-box motifs: 5'- CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer. Deletions in E2A have been observed in a subset of pre-B-cell acute lymphoblastic leukemia (B-ALL) cases. Two alternatively spliced human isoforms have been described.
Protein type: Oncoprotein; DNA-binding; Transcription factor
Cellular Component: nucleoplasm; transcription factor complex; protein complex; cytoplasm; nuclear chromatin; nucleus
Molecular Function: protein dimerization activity; protein homodimerization activity; transcription coactivator activity; mitogen-activated protein kinase kinase kinase binding; transcription factor binding; PDZ domain binding; protein binding; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; bHLH transcription factor binding; chromatin binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; Peyer's patch development; response to drug; nervous system development; transcription, DNA-dependent; protein stabilization; immunoglobulin V(D)J recombination; B cell lineage commitment; positive regulation of transcription, DNA-dependent; T cell differentiation in the thymus; positive regulation of cell cycle; gastrulation; response to lipopolysaccharide; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; lymphocyte differentiation; natural killer cell differentiation; positive regulation of B cell proliferation; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; cell differentiation; positive regulation of neuron differentiation; cell development
Research Articles on TCF3
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Product Notes
The Mouse TCF3 tcf3 (Catalog #AAA9331916) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331916 ELISA Kit recognizes Mouse TCF3. It is sometimes possible for the material contained within the vial of "transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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