Human transcription elongation regulator 1 ELISA Kit | TCERG1 elisa kit

Human Transcription elongation regulator 1, TCERG1 ELISA Kit

Cat. Num. AAA9320541

• Gene Names: TCERG1; Urn1; CA150; TAF2S
• Reactivity: Human
• Synonyms: transcription elongation regulator 1; Human Transcription elongation regulator 1; TCERG1 ELISA Kit; Human Transcription elongation regulator 1 (TCERG1) ELISA kit; CA150; MGC133200; TAF2S; TATA box binding protein (TBP) -associated factor; RNA polymerase II; S; 150kD; TATA box-binding protein-associated factor 2S; co-activator of 150 kDa; transcription factor CA15; TCERG1 elisa kit

• Reactivity: Human

• Assay Type: Quantitative Sandwich
• Detection Range: 0.5ng/ml-16ng/ml
• Sensitivity: 0.1ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for TCERG1 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used for determine the level of TCERG1 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 91208418
• NCBI GeneID: 10915
• NCBI Accession #: NP_001035095.1
• NCBI GenBank Nucleotide #: NM_001040006.1
• UniProt Accession #: O14776; Q2NKN2; Q59EA1
• Molecular Weight: 123,901 Da
• NCBI Official Full Name: transcription elongation regulator 1 isoform 2
• NCBI Official Synonym Full Names: transcription elongation regulator 1
• NCBI Official Symbol: TCERG1
• NCBI Official Synonym Symbols: Urn1; CA150; TAF2S
• NCBI Protein Information: transcription elongation regulator 1; co-activator of 150 kDa; transcription factor CA150; TATA box-binding protein-associated factor 2S; TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD
• UniProt Protein Name: Transcription elongation regulator 1
• Protein Family: Transcription elongation regulator
• UniProt Gene Name: TCERG1
• UniProt Synonym Gene Names: CA150; TAF2S
• UniProt Entry Name: TCRG1_HUMAN

NCBI Description

This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

TCERG1: Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Transcription factor; Spliceosome

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: nucleolus; nucleus; actin cytoskeleton

Molecular Function: protein binding; transcription coactivator activity

Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter