Rabbit anti-Human TCERG1 Polyclonal Antibody | anti-TCERG1 antibody

TCERG1, CT (TCERG1, CA150, TAF2S, Transcription elongation regulator 1, TATA box-binding protein-associated factor 2S, Transcription factor CA150)

Cat. Num. AAA6002623

• Gene Names: TCERG1; Urn1; CA150; TAF2S
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: TCERG1; Polyclonal Antibody; CT (TCERG1; CA150; TAF2S; Transcription elongation regulator 1; TATA box-binding protein-associated factor 2S; Transcription factor CA150); Anti -TCERG1; anti-TCERG1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-TCERG1 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: TCERG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 990-1020 amino acids from the C-terminal region of human TCERG1.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TCERG1 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TCERG1 antibody detected the TCERG1 protein (arrow).)

Related Product Information for anti-TCERG1 antibody

This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.

Product Categories/Family for anti-TCERG1 antibody

Antibodies; Abs to Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 91208418
• NCBI GeneID: 10915
• NCBI Accession #: NP_001035095.1
• NCBI GenBank Nucleotide #: NM_001040006.1
• UniProt Accession #: O14776; Q2NKN2; Q59EA1
• Molecular Weight: 123,901 Da
• NCBI Official Full Name: transcription elongation regulator 1 isoform 2
• NCBI Official Synonym Full Names: transcription elongation regulator 1
• NCBI Official Symbol: TCERG1
• NCBI Official Synonym Symbols: Urn1; CA150; TAF2S
• NCBI Protein Information: transcription elongation regulator 1; co-activator of 150 kDa; transcription factor CA150; TATA box-binding protein-associated factor 2S; TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD
• UniProt Protein Name: Transcription elongation regulator 1
• Protein Family: Transcription elongation regulator
• UniProt Gene Name: TCERG1
• UniProt Synonym Gene Names: CA150; TAF2S
• UniProt Entry Name: TCRG1_HUMAN

NCBI Description

This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

TCERG1: Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; RNA-binding; Spliceosome

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: nucleolus; nucleus; actin cytoskeleton

Molecular Function: protein binding; transcription coactivator activity

Biological Process: transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter