Human transcription elongation factor A (SII) , 1 ELISA Kit | TCEA1 elisa kit
Human Transcription elongation factor A protein 1, TCEA1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TFIIS: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. A chromosomal aberration involving TCEA1 may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(3;8)(p21;q12) with PLAG1. Belongs to the TFS-II family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 8q11.2
Cellular Component: nucleoplasm; nucleolus; nucleus
Molecular Function: protein binding; DNA binding; zinc ion binding
Biological Process: transcription from RNA polymerase II promoter; viral reproduction; positive regulation of viral transcription; nucleotide-excision repair; transcription-coupled nucleotide-excision repair; RNA elongation from RNA polymerase II promoter; erythrocyte differentiation; gene expression; positive regulation of transcription from RNA polymerase II promoter; DNA repair; regulation of RNA elongation
Research Articles on TCEA1
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Product Notes
The Human TCEA1 tcea1 (Catalog #AAA9326861) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9326861 ELISA Kit recognizes Human TCEA1. It is sometimes possible for the material contained within the vial of "transcription elongation factor A (SII) , 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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