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Western Blot (WB) (Western blot analysis of CAZIP in A20 cell lysate with CAZIP antibody at (A) 0.5 and (B) 1 ug/mL.)

Rabbit anti-Human, Mouse CAZIP Polyclonal Antibody | anti-CAZIP antibody

CAZIP Antibody

Gene Names
MTUS2; ICIS; CAZIP; TIP150; KIAA0774
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
CAZIP; Polyclonal Antibody; CAZIP Antibody; Cardiac zipper protein; Microtubule-associated tumor suppressor candidate 2; MTUS2; TIP150; anti-CAZIP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1379
Applicable Applications for anti-CAZIP antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against an 18 amino acid peptide near the carboxy terminus of human CAZIP.
Target Name
CAZIP
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of CAZIP in A20 cell lysate with CAZIP antibody at (A) 0.5 and (B) 1 ug/mL.)

Western Blot (WB) (Western blot analysis of CAZIP in A20 cell lysate with CAZIP antibody at (A) 0.5 and (B) 1 ug/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of CAZIP in mouse heart tissue with CAZIP antibody at 5 ug/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of CAZIP in mouse heart tissue with CAZIP antibody at 5 ug/mL.)
Related Product Information for anti-CAZIP antibody
CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
Product Categories/Family for anti-CAZIP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,064 Da
NCBI Official Full Name
microtubule-associated tumor suppressor candidate 2 isoform a
NCBI Official Synonym Full Names
microtubule associated tumor suppressor candidate 2
NCBI Official Symbol
MTUS2
NCBI Official Synonym Symbols
ICIS; CAZIP; TIP150; KIAA0774
NCBI Protein Information
microtubule-associated tumor suppressor candidate 2
UniProt Protein Name
Microtubule-associated tumor suppressor candidate 2
UniProt Gene Name
MTUS2
UniProt Synonym Gene Names
CAZIP; KIAA0774; TIP150; Tracking protein of 150 kDa
UniProt Entry Name
MTUS2_HUMAN

Uniprot Description

MTUS2: Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules. May regulate the dynamics of microtubules at their growing distal tip. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 13q12.3

Cellular Component: centrosome; cytoplasmic microtubule

Molecular Function: protein binding; protein homodimerization activity; microtubule binding

Research Articles on CAZIP

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Product Notes

The CAZIP mtus2 (Catalog #AAA9403967) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CAZIP Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CAZIP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the CAZIP mtus2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAZIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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