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CKAP1/TBCB Recombinant Protein | TBCB recombinant protein
CKAP1/TBCB Protein, Human, Recombinant (His Tag)
Gene Names
TBCB; CG22; CKAP1; CKAPI
Purity
>90% as determined by SDS-PAGE
Synonyms
CKAP1/TBCB; CKAP1/TBCB Protein; Human; Recombinant (His Tag); Human TBCB Protein (His Tag); CG22 Protein; CKAP1 Protein; CKAPI Protein; tubulin folding cofactor B; TBCB recombinant protein
Host
E Coli
Purity/Purification
>90% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Ile244
Species
Human
Predicted N Terminal
His
Tag
N-His
Protein Construction
A DNA sequence encoding the mature form of human TBCB (Q99426)(Met1-Ile244) was expressed with a polyhistide tag at the N-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
Related Product Information for TBCB recombinant protein
Background: Tubulin-folding cofactor B, also known as TBCB, belongs to the TBCB family. It contains 1 CAP-Gly domain and can be detected in most tissues. TBCB binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway. The cytoskeleton is composed of 3 structural elements: actin filaments, microtubules, and intermediate filaments. TBCB is involved in regulation of tubulin heterodimer dissociation. It may function as a negative regulator of axonal growth.
References
Feingold EA, et al. (2003) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903. Tian G, et al. (1997) Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors. J Cell Biol. 138(4):821-32. Wolz W, et al. (1997) A complex satellite DNA polymorphism flanking the human ryanodine receptor gene (RYR1). Cytogenet Cell Genet. 72(2-3):215-6.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
244
NCBI Official Full Name
Tubulin-folding cofactor B
NCBI Official Synonym Full Names
tubulin folding cofactor B
NCBI Official Symbol
TBCB
NCBI Official Synonym Symbols
CG22; CKAP1; CKAPI
NCBI Protein Information
tubulin-folding cofactor B; tubulin-specific chaperone B; cytoskeleton associated protein 1; cytoskeleton-associated protein CKAPI
UniProt Protein Name
Tubulin-folding cofactor B
UniProt Gene Name
TBCB
UniProt Synonym Gene Names
CG22; CKAP1
UniProt Entry Name
TBCB_HUMAN
Uniprot Description
TBCB: a cytoskeletal protein that binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer.
Protein type: Motility/polarity/chemotaxis; Chaperone; Cytoskeletal
Chromosomal Location of Human Ortholog: 19q13.11-q13.12
Cellular Component: microtubule cytoskeleton; nucleoplasm; microtubule; cytoplasm
Molecular Function: protein binding
Biological Process: nervous system development; 'de novo' posttranslational protein folding; cellular protein metabolic process; cell differentiation
Research Articles on TBCB
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Product Notes
The TBCB tbcb (Catalog #AAA8121653) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Ile24 4. It is sometimes possible for the material contained within the vial of "CKAP1/TBCB, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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