NCBI and Uniprot Product Information
NCBI Description
This gene encodes a key enzyme of the nonoxidative pentose phosphate pathway that provides ribose-5-phosphate for nucleic acid synthesis and nicotinamide adenine dinucleotide phosphate (NADPH) for lipid biosynthesis. The encoded protein is important for maintaining structure and function of mitochondria. Studies in knockout mice identify that deficiency of this gene product is a cause of sperm dysmotility and male infertility. Deficiency of this protein has also been identified as a cause of hepatocarcinogenesis in mice. Two related pseudogenes have been identified on chromosome 10. [provided by RefSeq, Mar 2010]
Uniprot Description
TALDO1: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency). It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Belongs to the transaldolase family. Type 1 subfamily.
Protein type: Carbohydrate Metabolism - pentose phosphate pathway; EC 2.2.1.2; Transferase
Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleus
Molecular Function: carbohydrate binding; catalytic activity; monosaccharide binding; transaldolase activity; transferase activity
Biological Process: carbohydrate metabolic process; fructose 6-phosphate metabolic process; glyceraldehyde-3-phosphate metabolic process; pentose-phosphate shunt; pentose-phosphate shunt, non-oxidative branch
Research Articles on Taldo1
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Product Notes
The Mouse Taldo1 taldo1 (Catalog #AAA289474) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289474 ELISA Kit recognizes Mouse Taldo1. It is sometimes possible for the material contained within the vial of "Transaldolase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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