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Typical Testing Data/Standard Curve (for reference only)

Canine Thrombin activatable fibrinolysis inhibitor ELISA Kit | TAFI elisa kit

Canine Thrombin activatable fibrinolysis inhibitor (TAFI) ELISA Kit

Gene Names
Cpb2; CPR; Cpu; TAFI; AI255929; 1110032P04Rik; 4930405E17Rik
Reactivity
Canine
Synonyms
Thrombin activatable fibrinolysis inhibitor; Canine Thrombin activatable fibrinolysis inhibitor (TAFI) ELISA Kit; TAFI elisa kit
Ordering
For Research Use Only!
Reactivity
Canine
Specificity
No cross-reaction with other factors.
Sequence Length
422
Samples
Canine Serum, Plasma Or Cell Culture Supernatant And Organizations In The Natural And Recombinant Sp Concentration
Assay Type
Sandwich
Detection Range
1000 pg/ml-15.6pg/ml
Sensitivity
5 pg/ml.
Intra-assay Precision
<= 8%
Inter-assay Precision
<= 12%
Preparation and Storage
Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for TAFI elisa kit
Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is Canine SP monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
48,871 Da
NCBI Official Full Name
thrombin-activatable fibrinolysis inhibitor
NCBI Official Synonym Full Names
carboxypeptidase B2 (plasma)
NCBI Official Symbol
Cpb2
NCBI Official Synonym Symbols
CPR; Cpu; TAFI; AI255929; 1110032P04Rik; 4930405E17Rik
NCBI Protein Information
carboxypeptidase B2
UniProt Protein Name
Carboxypeptidase B2
UniProt Gene Name
Cpb2
UniProt Synonym Gene Names
Tafi; CPR; CPU; TAFI
UniProt Entry Name
CBPB2_MOUSE

NCBI Description

This gene encodes carboxypeptidase B, a zinc-dependent metalloprotease that cleaves peptide bonds at the C-terminus of protein substrates. The encoded preproprotein undergoes proteolytic activation to generate a mature, functional enzyme, and secreted into plasma. [provided by RefSeq, Jan 2016]

Uniprot Description

CPB2: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. Belongs to the peptidase M14 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.17.20

Cellular Component: extracellular region; extracellular space

Molecular Function: carboxypeptidase activity; hydrolase activity; metal ion binding; metallocarboxypeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding

Biological Process: blood coagulation; fibrinolysis; hemostasis; negative regulation of fibrinolysis; proteolysis; response to heat

Research Articles on TAFI

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Product Notes

The Canine TAFI cpb2 (Catalog #AAA2604308) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2604308 ELISA Kit recognizes Canine TAFI. It is sometimes possible for the material contained within the vial of "Thrombin activatable fibrinolysis inhibitor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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