Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase Recombinant Protein | TACO1 recombinant protein
Recombinant Human Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase
Gene Names
TACO1; CCDC44
Purity
Greater than 95% as determined by SDS-PAGE.
Synonyms
Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase; Recombinant Human Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase; TACO1 Human; Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase Human Recombinant; Translational Activator Of Mitochondrially Encoded Cytochrome C Oxidase; CCDC44; Coiled-Coil Domain-Containing Protein 44; Coiled-Coil Domain Containing 44; Clone HQ0477 PRO0477p; Translational Activator Of Cytochrome C Oxidase 1; Translational Activator Of Mitochondrially-Encoded Cytochrome C Oxidase I; TACO1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
TACO1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSNKWSKVR HIKGPKDVER SRIFSKLCLN IRLAVKEGGP NPEHNSNLAN ILEVCRSKHM PKSTIETALK MEKSKDTYLL YEGRGPGGSS LLIEALSNSS HKCQADIRHI LNKNGGVMAV GARHSFDKKG VIVVEVEDRE KKAVNLERAL EMAIEAGAEDVKETEDEEER NVFKFICDAS SLHQVRKKLD SLGLCSVSCA LEFIPNSKVQ LAEPDLEQAA HLIQALSNHE DVIHVYDNIE
Sequence Length
297
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Related Product Information for TACO1 recombinant protein
Description: TACO1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 260 amino acids (61-297 a.a) and having a molecular mass of 28.8kDa.TACO1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Translational activator of mitochondrially encoded cytochrome c oxidase I (TACO1) belongs to the TACO1 family. TACO1 is a mitochondrial protein which functions as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.
Introduction: Translational activator of mitochondrially encoded cytochrome c oxidase I (TACO1) belongs to the TACO1 family. TACO1 is a mitochondrial protein which functions as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.
Product Categories/Family for TACO1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,477 Da
NCBI Official Full Name
translational activator of cytochrome c oxidase 1
NCBI Official Synonym Full Names
translational activator of mitochondrially encoded cytochrome c oxidase I
NCBI Official Symbol
TACO1
NCBI Official Synonym Symbols
CCDC44
NCBI Protein Information
translational activator of cytochrome c oxidase 1; clone HQ0477 PRO0477p; coiled-coil domain-containing protein 44
UniProt Protein Name
Translational activator of cytochrome c oxidase 1
Protein Family
UniProt Gene Name
TACO1
UniProt Synonym Gene Names
CCDC44
UniProt Entry Name
TACO1_HUMAN
NCBI Description
This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010]
Uniprot Description
CCDC44: Acts as a translational activator of mitochondrially- encoded cytochrome c oxidase 1. Defects in TACO1 are a cause of Leigh syndrome (LS). LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency. Belongs to the TACO1 family.
Chromosomal Location of Human Ortholog: 17q23.3
Cellular Component: nucleoplasm; mitochondrion; nucleus
Biological Process: regulation of translation
Disease: Mitochondrial Complex Iv Deficiency
Research Articles on TACO1
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Product Notes
The TACO1 taco1 (Catalog #AAA146405) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSNKW SKVR HIKGPKDVER SRIFSKLCLN IRLAVKEGGP NPEHNSNLAN ILEVCRSKHM PKSTIETALK MEKSKDTYLL YEGRGPGGSS LLIEALSNSS HKCQADIRHI LNKNGGVMAV GARHSFDKKG VIVVEVEDRE KKAVNLERAL EMAIEAGAED VKETEDEEER NVFKFICDAS SLHQVRKKLD SLGLCSVSCA LEFIPNSKVQ LAEPDLEQAA HLIQALSNHE DVIHVYDNIE. It is sometimes possible for the material contained within the vial of "Translational Activator of Mitochondrially Encoded Cytochrome C Oxidase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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