Synaptotagmin-12 (SYT12) Recombinant Protein | SYT12 recombinant protein
Recombinant Human Synaptotagmin-12 (SYT12), partial
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.[provided by RefSeq, Apr 2010]
Uniprot Description
May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis.
Research Articles on SYT12
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Product Notes
The SYT12 syt12 (Catalog #AAA1352383) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 40-421. The amino acid sequence is listed below: W KLWTSGSFPS PSPFPNYDYR YLQQKYGESC AEAREKRVPA WNAQRASTRG PPSRKGSLSI EDTFESISEL GPLELMGREL DLAPYGTLRK SQSADSLNSI SSVSNTFGQD FTLGQVEVSM EYDTASHTLN VAVMQGKDLL EREEASFESC FMRVSLLPDE QIVGISRIQR NAYSIFFDEK FSIPLDPTAL EEKSLRFSVF GIDEDERNVS TGVVELKLSV LDLPLQPFSG WLYLQDQNKA ADAVGEILLS LSYLPTAERL TVVVVKAKNL IWTNDKTTAD PFVKVYLLQD GRKMSKKKTA VKRDDPNPVF NEAMIFSVPA IVLQDLSLRV TVAESSSDGR GDNVGHVIIG PSASGMGTTH WNQMLATLRR PVSMWHAVRR N. It is sometimes possible for the material contained within the vial of "Synaptotagmin-12 (SYT12), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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