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Chemical Structure (Chemical structure of JC-1 , a Mitochondrial membrane potential dependent fluorescent dye. CAS #: 3520-43-2. Molecular Formula: C25H27Cl4IN4. Molecular Weight: 652.2 g/mol.)

JC-1 small molecule

JC-1

Purity
>98% (HPLC); NMR (Conforms)
Synonyms
JC-1; Mitochondrial membrane-potential dependent fluorescent dye; 5; 6; 6-Tetrachloro-1; 1; 3; 3-tetraethylbenzimidazolylcarbocyanine iodide; 6-dichloro-2-[(E)-3-(5; 6-dichloro-1; 3-diethylbenzimidazol-3-ium-2-yl)prop-2-enylidene]-1; 3-diethylbenzimidazole;iodide; Jc-1; 3520-43-2; JC-1 jodide; JC1 dye; CBIC2(3); 5'; 6'-Tetrachloro-1; 1'; 3'-tetraethylbenzimidazolocarbocyanine iodide; JC-1 small molecule
Ordering
For Research Use Only!
Host
Synthetic
Purity/Purification
>98% (HPLC); NMR (Conforms)
Form/Format
Red powder
Solubility
May be dissolved in water (50 mg/ml); DMSO (15 mg/ml)
CAS Number
3520-43-2
Molecular Formula
C25H27Cl4IN4
SMILES
CCN1C2=CC(=C(C=C2[N+](=C1C=CC=C3N(C4=CC(=C(C=C4N3CC)Cl)Cl)CC)CC)Cl)Cl.[I-]
InChI
1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1
InChI Key
FYNNIUVBDKICAX-UHFFFAOYSA-M
PubChem CID
5492929
Preparation and Storage
Store at -20 degree C.

Chemical Structure

(Chemical structure of JC-1 , a Mitochondrial membrane potential dependent fluorescent dye. CAS #: 3520-43-2. Molecular Formula: C25H27Cl4IN4. Molecular Weight: 652.2 g/mol.)

Chemical Structure (Chemical structure of JC-1 , a Mitochondrial membrane potential dependent fluorescent dye. CAS #: 3520-43-2. Molecular Formula: C25H27Cl4IN4. Molecular Weight: 652.2 g/mol.)
Related Product Information for JC-1 small molecule
JC-1 is a fluorescent dye that is able to pass across the mitochondrial membrane. It is used to measure mitochondrial membrane potential. At low membrane potentials, it remains a monomer and emits green-fluorescent light (lambdaex=485 nm, lambdaem=520 nm). At higher membrane potentials, it forms "J-aggregates", which emit red-fluorescent light (lambdaex=520-570 nm, lambdaem=570-610 nm). The ratio of red/green fluorescence is based only on the membrane potential, and not on mitochondrial size, shape or density.

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Product Notes

The JC-1 (Catalog #AAA808256) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "JC-1, Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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