Structure
Neuromedin B Peptide | NMB peptide
Biotin-Neuromedin B
Structure
Structure
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Uniprot Description
NMB: Stimulates smooth muscle contraction in a manner similar to that of bombesin. Belongs to the bombesin/neuromedin-B/ranatensin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 15q22-qter
Cellular Component: cytosol; extracellular region; neuron projection
Molecular Function: hormone activity; neuromedin B receptor binding; protein binding
Biological Process: arachidonic acid secretion; cell-cell signaling; elevation of cytosolic calcium ion concentration; glucose homeostasis; negative regulation of hormone secretion; neuropeptide signaling pathway; positive regulation of cell proliferation; positive regulation of hormone secretion; signal transduction
Research Articles on NMB
Similar Products
Product Notes
The NMB nmb (Catalog #AAA8246266) is a Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Biotin-Gly -Asn-Leu-T rp-Ala-Thr -Gly-His-P he-Met-NH2. It is sometimes possible for the material contained within the vial of "Neuromedin B, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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