Structure
Glycogen Synthase Peptide | GYS2 peptide
Glycogen Synthase (1-8)
Structure
Structure
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content. [provided by RefSeq, Dec 2009]
Uniprot Description
GYS2: Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. Defects in GYS2 are the cause of glycogen storage disease type 0 (GSD0); A metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood, high blood ketones and low alanine and lactate concentrations. Although feeding relieves symptoms, it often results in postprandial hyperglycemia and hyperlactatemia. Belongs to the glycosyltransferase 3 family.
Protein type: EC 2.4.1.11; Transferase; Cytoskeletal; Carbohydrate Metabolism - starch and sucrose
Chromosomal Location of Human Ortholog: 12p12.2
Cellular Component: cell cortex; cortical actin cytoskeleton; cytoplasm; cytoskeleton; cytosol; ectoplasm
Molecular Function: glucose binding; glycogen (starch) synthase activity; protein homodimerization activity
Biological Process: generation of precursor metabolites and energy; glycogen biosynthetic process; response to glucose stimulus
Disease: Glycogen Storage Disease 0, Liver
Research Articles on GYS2
Similar Products
Product Notes
The GYS2 gys2 (Catalog #AAA8246526) is a Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Pro-Leu-Se r-Arg-Thr- Leu-Ser-Va l-Ala-Ala- Lys-Lys-NH 2. It is sometimes possible for the material contained within the vial of "Glycogen Synthase, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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