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Enkephalin Peptide | Penk peptide

Enkephalin (Leu)-[D-Ser2]-Thr (DSLET, Delta-Receptor Peptide)

Gene Names
Penk; Enk; Penk1; Penk2; Penk-rs
Purity
Highly Purified
~95%. Purified by HPLC.
Synonyms
Enkephalin; Enkephalin (Leu)-[D-Ser2]-Thr (DSLET; Delta-Receptor Peptide); Penk peptide
Ordering
For Research Use Only!
Host
Synthetic peptide
Purity/Purification
Highly Purified
~95%. Purified by HPLC.
Form/Format
Supplied as a lyophilized powder.
Sequence (linear)
Tyr-D-Ser-Gly-Phe-Leu-Thr
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Product Categories/Family for Penk peptide

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
30,932 Da
NCBI Official Full Name
enkephalin
NCBI Official Synonym Full Names
proenkephalin
NCBI Official Symbol
Penk
NCBI Official Synonym Symbols
Enk; Penk1; Penk2; Penk-rs
NCBI Protein Information
proenkephalin-A; proenkephalin 1; proenkephalin 2; preproenkephalin 2; proenkephalin related sequence
UniProt Protein Name
Proenkephalin-A
Protein Family
UniProt Gene Name
Penk
UniProt Synonym Gene Names
Penk-rs; Penk1; OGF
UniProt Entry Name
PENK_RAT

NCBI Description

neuropeptide hormone; plays a role in the responses to stress and pain perception [RGD, Feb 2006]

Uniprot Description

Function: Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(239-260) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum. Ref.8

Subcellular location: Secreted.

Tissue specificity: Expressed in brain, heart and testis.

Post-translational modification: The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing.

Sequence similarities: Belongs to the opioid neuropeptide precursor family.

Mass spectrometry: Molecular mass is 2203.971 Da from positions 114 - 133. Determined by ESI. Ref.8Molecular mass is 4592.8 Da from positions 143 - 185. Determined by ESI. Ref.8Molecular mass is 2504.027 Da from positions 239 - 260. Determined by ESI. Ref.8

Research Articles on Penk

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Product Notes

The Penk penk (Catalog #AAA659708) is a Peptide produced from Synthetic peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Enkephalin, Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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