NCBI Description
The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
TRPM3: a transient receptor potential (TRP) ion channel. Mediates constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by calcium store depletion and muscarinic receptor activation. TRP voltage-independent calcium-permeable cation channels are divided into six subfamilies, two of which (TRPC and TRPM) have members that are widely expressed. Ten alternatively spliced isoforms have been described.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation
Chromosomal Location of Human Ortholog: 9q21.12
Cellular Component: integral to membrane; plasma membrane
Molecular Function: calcium channel activity; cation channel activity; calcium activated cation channel activity
Biological Process: detection of temperature stimulus; sensory perception of temperature stimulus; transmembrane transport; cation transport
Product Notes
The TRPM3 trpm3 (Catalog #
AAA8207908) is a siRNA produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The TRPM3 siRNA (Human) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRPM3 can be used in a range of immunoassay formats including, but not limited to, RNA Interference (RNAi). Researchers should empirically determine the suitability of the TRPM3 trpm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"TRPM3, siRNA" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
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responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
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