TMPRSS13 sirna

TMPRSS13 siRNA (Human)

Cat. Num. AAA8220204

• Gene Names: TMPRSS13; MSP; MSPL; MSPS; TMPRSS11
• Reactivity: Human
• Applications: RNA Interference (RNAi)
• Purity: > 97%
• Synonyms: TMPRSS13; TMPRSS13 siRNA (Human); MSP; TMPRSS11; Transmembrane protease serine 13; Membrane-type mosaic serine protease; Mosaic serine protease; TMPRSS13 sirna

• Host: Synthetic
• Reactivity: Human
• Specificity: TMPRSS13 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
• Purity/Purification: > 97%
• Form/Format: Lyophilized powder
• Sequence Length: 532

• Applicable Applications for TMPRSS13 sirna: RNA Interference (RNAi)
• Quality Control: Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
• Directions for Use: We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
• Components: We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human TMPRSS13 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for TMPRSS13 sirna

siRNA to inhibit TMPRSS13 expression using RNA interference

NCBI and Uniprot Product Information

• NCBI GI #: 332205854
• NCBI GeneID: 84000
• NCBI Accession #: NP_001193718.1
• NCBI GenBank Nucleotide #: NM_001206789.1
• UniProt Accession #: Q9BYE2; Q86YM4; Q96JY8; Q9BYE1; B4DTM9; E9PIJ5; F8WAJ3
• Molecular Weight: 52,560 Da
• NCBI Official Full Name: transmembrane protease serine 13 isoform 2
• NCBI Official Synonym Full Names: transmembrane protease, serine 13
• NCBI Official Symbol: TMPRSS13
• NCBI Official Synonym Symbols: MSP; MSPL; MSPS; TMPRSS11
• NCBI Protein Information: transmembrane protease serine 13
• UniProt Protein Name: Transmembrane protease serine 13
• Protein Family: Transmembrane protease serine
• UniProt Gene Name: TMPRSS13
• UniProt Synonym Gene Names: MSP; TMPRSS11; Mosaic serine protease
• UniProt Entry Name: TMPSD_HUMAN

NCBI Description

This gene encodes a member of the type II transmembrane serine protease family. Transmembrane serine proteases are regulated by protease inhibitors and known to function in development, homeostasis, infection, and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

TMPRSS13: a member of the type II transmembrane serine protease family. Transmembrane serine proteases are regulated by protease inhibitors and known to function in development, homeostasis, infection, and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Protein type: Membrane protein, integral; EC 3.4.21.-; Protease

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: integral to membrane

Molecular Function: serine-type endopeptidase activity; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; proteolysis