OR2B3 sirna

OR2B3 siRNA (Human)

Cat. Num. AAA8221127

• Gene Names: OR2B3; 6M1-1; OR6-4; OR2B3P; OR6-14
• Reactivity: Human
• Applications: RNA Interference (RNAi)
• Purity: > 97%
• Synonyms: OR2B3; OR2B3 siRNA (Human); OR2B3P; Putative olfactory receptor 2B3; Hs6M1-1; Olfactory receptor OR6-14; OR6-4; Olfactory receptor 6-4; OR2B3 sirna

• Host: Synthetic
• Reactivity: Human
• Specificity: OR2B3 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
• Purity/Purification: > 97%
• Form/Format: Lyophilized powder
• Sequence Length: 313

• Applicable Applications for OR2B3 sirna: RNA Interference (RNAi)
• Quality Control: Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
• Directions for Use: We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
• Components: We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human OR2B3 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for OR2B3 sirna

siRNA to inhibit OR2B3 expression using RNA interference

NCBI and Uniprot Product Information

• NCBI GI #: 52421347
• NCBI GeneID: 442184
• NCBI Accession #: NP_001005226.1
• NCBI GenBank Nucleotide #: NM_001005226.2
• UniProt Accession #: O76000; Q5ST41; Q96R13; B0UYQ1
• Molecular Weight: 35,543 Da
• NCBI Official Full Name: putative olfactory receptor 2B3
• NCBI Official Synonym Full Names: olfactory receptor, family 2, subfamily B, member 3
• NCBI Official Symbol: OR2B3
• NCBI Official Synonym Symbols: 6M1-1; OR6-4; OR2B3P; OR6-14
• NCBI Protein Information: putative olfactory receptor 2B3
• UniProt Protein Name: Putative olfactory receptor 2B3
• Protein Family: Putative olfactory receptor
• UniProt Gene Name: OR2B3
• UniProt Synonym Gene Names: OR2B3P; OR6-4; Olfactory receptor 6-4
• UniProt Entry Name: OR2B3_HUMAN

NCBI Description

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Uniprot Description

OR2B3P: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 6p22.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; olfactory receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell