Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

MRPL39 sirna

MRPL39 siRNA (Human)

Gene Names
MRPL39; L39mt; MRPL5; RPML5; MRP-L5; PRED22; PRED66; MSTP003; C21orf92
Reactivity
Human
Applications
RNA Interference (RNAi)
Purity
> 97%
Synonyms
MRPL39; MRPL39 siRNA (Human); C21orf92; MRPL5; RPML5; 39S ribosomal protein L39 mitochondrial; L39mt; MRP-L39; 39S ribosomal protein L5 mitochondrial; L5mt; MRP-L5; MRPL39 sirna
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human
Specificity
MRPL39 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Purity/Purification
> 97%
Form/Format
Lyophilized powder
Sequence Length
353
Applicable Applications for MRPL39 sirna
RNA Interference (RNAi)
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Directions for Use
We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
Components
We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human MRPL39 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for MRPL39 sirna
siRNA to inhibit MRPL39 expression using RNA interference

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
40,458 Da
NCBI Official Full Name
39S ribosomal protein L39, mitochondrial isoform a
NCBI Official Synonym Full Names
mitochondrial ribosomal protein L39
NCBI Official Symbol
MRPL39
NCBI Official Synonym Symbols
L39mt; MRPL5; RPML5; MRP-L5; PRED22; PRED66; MSTP003; C21orf92
NCBI Protein Information
39S ribosomal protein L39, mitochondrial
UniProt Protein Name
39S ribosomal protein L39, mitochondrial
Protein Family
UniProt Gene Name
MRPL39
UniProt Synonym Gene Names
C21orf92; MRPL5; RPML5; L39mt; MRP-L39; L5mt; MRP-L5
UniProt Entry Name
RM39_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPL39: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Translation; Mitochondrial; Ribosomal

Chromosomal Location of Human Ortholog: 21q21.3

Cellular Component: mitochondrial inner membrane; mitochondrial ribosome

Molecular Function: nucleotide binding

Biological Process: mitochondrial translation; organelle organization and biogenesis

Research Articles on MRPL39

Similar Products

Product Notes

The MRPL39 mrpl39 (Catalog #AAA8237324) is a siRNA produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The MRPL39 siRNA (Human) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MRPL39 can be used in a range of immunoassay formats including, but not limited to, RNA Interference (RNAi). Researchers should empirically determine the suitability of the MRPL39 mrpl39 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRPL39, siRNA" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.