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ZHX2 blocking peptide

ZHX2 Blocking Peptide

Gene Names
ZHX2; RAF; AFR1
Reactivity
Human, Mouse, Rat, Monkey
Applications
Blocking (BL)
Purity
>85%
Synonyms
ZHX2; ZHX2 Blocking Peptide; AFR1; KIAA0854; RAF; Zinc fingers and homeoboxes protein 2; Alpha-fetoprotein regulator 1; AFP regulator 1; Regulator of AFP; Zinc finger and homeodomain protein 2; ZHX2 blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human, Mouse, Rat, Monkey
Purity/Purification
>85%
Form/Format
Lyophilized powder
Sequence Length
837
Applicable Applications for ZHX2 blocking peptide
Blocking (BL)
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Directions for Use
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for ZHX2 blocking peptide
The peptide is used to block Anti-ZHX2 Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
92,307 Da
NCBI Official Full Name
zinc fingers and homeoboxes protein 2
NCBI Official Synonym Full Names
zinc fingers and homeoboxes 2
NCBI Official Symbol
ZHX2
NCBI Official Synonym Symbols
RAF; AFR1
NCBI Protein Information
zinc fingers and homeoboxes protein 2
UniProt Protein Name
Zinc fingers and homeoboxes protein 2
UniProt Gene Name
ZHX2
UniProt Synonym Gene Names
AFR1; KIAA0854; RAF; AFP regulator 1
UniProt Entry Name
ZHX2_HUMAN

NCBI Description

The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008]

Uniprot Description

ZHX2: Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. Belongs to the ZHX family.

Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 8q24.13

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; DNA binding; protein heterodimerization activity; metal ion binding; transcription corepressor activity; transcription factor activity

Biological Process: negative regulation of neuron differentiation; transcription, DNA-dependent; somatic stem cell maintenance; mRNA catabolic process; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent

Research Articles on ZHX2

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Product Notes

The ZHX2 zhx2 (Catalog #AAA8226515) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The ZHX2 Blocking Peptide reacts with Human, Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's ZHX2 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Researchers should empirically determine the suitability of the ZHX2 zhx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZHX2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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