PAOX blocking peptide
PAOX Blocking Peptide
NCBI and Uniprot Product Information
Uniprot Description
PAOX: Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. Belongs to the flavin monoamine oxidase family. 11 isoforms of the human protein are produced by alternative splicing.
Protein type: Oxidoreductase; EC 1.5.3.13
Chromosomal Location of Human Ortholog: 10q26.3
Cellular Component: peroxisomal matrix
Molecular Function: receptor binding; polyamine oxidase activity
Biological Process: spermine catabolic process; polyamine biosynthetic process; putrescine biosynthetic process; xenobiotic metabolic process; polyamine catabolic process; spermidine catabolic process; putrescine catabolic process; polyamine metabolic process
Research Articles on PAOX
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Product Notes
The PAOX paox (Catalog #AAA823268) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The PAOX Blocking Peptide reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PAOX can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the PAOX paox for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAOX, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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