EID1 blocking peptide

EID1 Blocking Peptide

Gene Names

EID1; CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620

Reactivity

Human, Bovine

Applications

Blocking (BL)

Purity

>85%

Synonyms

EID1; EID1 Blocking Peptide; C15orf3; CRI1; RBP21; EP300-interacting inhibitor of differentiation 1; 21 kDa pRb-associated protein; CREBBP/EP300 inhibitory protein 1; E1A-like inhibitor of differentiation 1; EID-1; EID1 blocking peptide

Ordering
Cat. Num. AAA8247840 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Host

Synthetic

Reactivity

Human, Bovine

Purity/Purification

>85%

Form/Format

Lyophilized powder

Sequence Length

187

Applicable Applications for EID1 blocking peptide

Blocking (BL)

Application Notes

Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.

Quality Control

The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.

Preparation and Storage

Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for EID1 blocking peptide

The peptide is used to block Anti-EID1 Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #

7656938

NCBI GeneID

23741

NCBI Accession #

NP_055150.1

NCBI GenBank Nucleotide #

NM_014335.2

UniProt Accession #

Q9Y6B2; Q8N7I4; Q9BZT9; B2RD11

Molecular Weight

18,616 Da

NCBI Official Full Name

EP300-interacting inhibitor of differentiation 1

NCBI Official Synonym Full Names

EP300 interacting inhibitor of differentiation 1

NCBI Official Symbol

EID1

NCBI Official Synonym Symbols

CRI1; EID-1; RBP21; PTD014; C15orf3; PNAS-22; IRO45620

NCBI Protein Information

EP300-interacting inhibitor of differentiation 1

UniProt Protein Name

EP300-interacting inhibitor of differentiation 1

Protein Family

EID1-like F-box protein

UniProt Gene Name

EID1

UniProt Synonym Gene Names

EID-1

UniProt Entry Name

EID1_HUMAN

Uniprot Description

EID1: Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q21.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: histone acetyltransferase binding; histone acetyltransferase regulator activity; protein binding; transcription corepressor activity

Biological Process: cell differentiation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent

Research Articles on EID1

1. SCF(FBXO21) polyubiquitylates EID1 both in vitro and in vivo and is required for the efficient degradation of EID1 in both cycling and quiescent cells.

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Product Notes

The EID1 eid1 (Catalog #AAA8247840) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The EID1 Blocking Peptide reacts with Human, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's EID1 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the EID1 eid1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EID1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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EID1 blocking peptide