Histone-lysine N-methyltransferase SUVR2 (SUVR2) Recombinant Protein | SUVR2 recombinant protein

Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase SUVR2 (SUVR2) , partial

• Gene Names: SUVR2; MRH10.10; MRH10_10; SDG18; SET DOMAIN PROTEIN 18
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Histone-lysine N-methyltransferase SUVR2 (SUVR2); Recombinant Arabidopsis thaliana Histone-lysine N-methyltransferase SUVR2 (SUVR2); partial; SUVR2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 717

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 145334713
• NCBI GeneID: 834422
• NCBI Accession #: NP_001078702.1
• NCBI GenBank Nucleotide #: NM_001085233.2
• UniProt Accession #: Q9FNC7; Q0WKU5; Q941L4
• Molecular Weight: 79,363 Da
• NCBI Official Full Name: SET-domain containing protein lysine methyltransferase family protein
• NCBI Official Symbol: SUVR2
• NCBI Official Synonym Symbols: MRH10.10; MRH10_10; SDG18; SET DOMAIN PROTEIN 18
• NCBI Protein Information: SET-domain containing protein lysine methyltransferase family protein
• UniProt Protein Name: Probable inactive histone-lysine N-methyltransferase SUVR2
• Protein Family: Probable inactive histone-lysine N-methyltransferase
• UniProt Gene Name: SUVR2
• UniProt Synonym Gene Names: SDG18; SET18; Su(var)3-9-related protein 2

NCBI Description

Encodes SUVR2, one of the four closely related Arabidopsis SUVR proteins that belong to the SU(VAR)3-9 subgroup of SET-domain proteins. Proteins containing the evolutionarily conserved SET domain are involved in regulation of eukaryotic gene expression and chromatin structure through their histone lysine methyltransferase (HMTase) activity. SUVR1, SUVR2 and SUVR4 proteins contain a novel domain at their N-terminus, and a SUVR specific region preceding the SET domain. Localized to the nucleolus, maybe involved in regulation of rRNA expression.

Uniprot Description

Probable inactive histone-lysine methyltransferase that acts as regulator of transctiptional gene silencing independently of histone H3K9 methylation. Contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. Forms a complex with SUVR1 and associates with the SNF2-related chromatin-remodeling proteins CHR19, CHR27, and CHR28, thereby mediating nucleosome positioning and transcriptional silencing. Does not possess histone-lysine methyltransferase activity in vitro, and the conserved catalytic sites of SUVR2 are dispensable for its function in transcriptional gene silencing.