Mouse suppressor of variegation 4-20 homolog 2 (Drosophila) ELISA Kit | SUV420H2 elisa kit
Mouse Histone-lysine N-methyltransferase SUV420H2, SUV420H2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SUV420H2: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Belongs to the histone-lysine methyltransferase family. Suvar4-20 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Methyltransferase, protein lysine; Amino Acid Metabolism - lysine degradation; EC 2.1.1.43; Methyltransferase
Cellular Component: nucleoplasm; centric heterochromatin; chromosome; nuclear heterochromatin; nucleus; condensed nuclear chromosome, pericentric region
Molecular Function: transferase activity; methyltransferase activity; histone lysine N-methyltransferase activity (H4-K20 specific); histone-lysine N-methyltransferase activity
Biological Process: histone methylation; methylation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; chromatin modification; peptidyl-lysine methylation
Research Articles on SUV420H2
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Product Notes
The Mouse SUV420H2 suv420h2 (Catalog #AAA9330303) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9330303 ELISA Kit recognizes Mouse SUV420H2. It is sometimes possible for the material contained within the vial of "suppressor of variegation 4-20 homolog 2 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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