Histone-lysine N-methyltransferase SUV39H1 (suv39h1) Recombinant Protein | suv39h1 recombinant protein
Recombinant Xenopus laevis Histone-lysine N-methyltransferase SUV39H1 (suv39h1)
Gene Names
suv39h1.L; kmt1a; suv39h; suv39h1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Histone-lysine N-methyltransferase SUV39H1 (suv39h1); Recombinant Xenopus laevis Histone-lysine N-methyltransferase SUV39H1 (suv39h1); suv39h1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-421, Full length protein
Sequence
MAENSNGALGCVVRCLSSESELQELCREEQLCCAELGVTRKNLSDFEVEYLWNYKKVQDQELYLVKWKYYPDSESTWEPRHHLKCNNLLKQFHLDLERELLRRAKAAGTKKTAVRCPRRLDQSLSHYLVLKAKQRKRLRQWAQQLNAKRSHLGLILVENEVDLEGPPRDFVYINEYRVGEGVTINRISAGCKCRDCFSDEGGCCPGAFQHKKAYNNEGQVKVKPGFPIYECNSCCRCGPSCPNRVVQKGIQYKFCIFRTSDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGTTYLFDLDYVEDVYTVDAARYGNISHFVNHSCKPNLQVYNVFIDNLDERLPRIAFFATRTIRTGEELTFDYNMQVDPVDVESSKMDSNFGIAGLPASPKKRVRVECKCGVSSCRKYLF
Sequence Length
421
Species
Xenopus laevis (African clawed frog)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48,581 Da
NCBI Official Full Name
histone-lysine N-methyltransferase SUV39H1
NCBI Official Synonym Full Names
suppressor of variegation 3-9 homolog 1 L homeolog
NCBI Official Symbol
suv39h1.L
NCBI Official Synonym Symbols
kmt1a; suv39h; suv39h1
NCBI Protein Information
histone-lysine N-methyltransferase SUV39H1
UniProt Protein Name
Histone-lysine N-methyltransferase SUV39H1
Protein Family
UniProt Gene Name
suv39h1
UniProt Synonym Gene Names
Su(var)3-9 homolog 1
Uniprot Description
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes ().
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Product Notes
The suv39h1 suv39h1 (Catalog #AAA1480554) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-421, Full length protein. The amino acid sequence is listed below: MAENSNGALG CVVRCLSSES ELQELCREEQ LCCAELGVTR KNLSDFEVEY LWNYKKVQDQ ELYLVKWKYY PDSESTWEPR HHLKCNNLLK QFHLDLEREL LRRAKAAGTK KTAVRCPRRL DQSLSHYLVL KAKQRKRLRQ WAQQLNAKRS HLGLILVENE VDLEGPPRDF VYINEYRVGE GVTINRISAG CKCRDCFSDE GGCCPGAFQH KKAYNNEGQV KVKPGFPIYE CNSCCRCGPS CPNRVVQKGI QYKFCIFRTS DGRGWGVRTL EKIRKNSFVM EYVGEIITSE EAERRGQIYD RQGTTYLFDL DYVEDVYTVD AARYGNISHF VNHSCKPNLQ VYNVFIDNLD ERLPRIAFFA TRTIRTGEEL TFDYNMQVDP VDVESSKMDS NFGIAGLPAS PKKRVRVECK CGVSSCRKYL F. It is sometimes possible for the material contained within the vial of "Histone-lysine N-methyltransferase SUV39H1 (suv39h1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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