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Protein suppressor of hairless (Su (H)) Recombinant Protein | Su(H) recombinant protein

Recombinant Drosophila simulans Protein suppressor of hairless (Su (H))

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Protein suppressor of hairless (Su (H)); Recombinant Drosophila simulans Protein suppressor of hairless (Su (H)); Su(H) recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-102, Full length protein
Sequence
NPNGSPLDPHQQQQQQQSQDMPHFGLPGPQPPSSQQQQQQMQVHHQQQQQQQQQQQHQQQMQMSLLPGPYRPHIEEKKLTRDAMEKYMRERNDMVIVILHAK
Sequence Length
102
Species
Drosophila simulans (Fruit fly)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
12,089 Da
NCBI Official Full Name
Protein suppressor of hairless
UniProt Protein Name
Protein suppressor of hairless
UniProt Gene Name
Su(H)

Uniprot Description

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Binds directly the 5'-GTGRGAR-3' DNA consensus sequence, which is present in the regulatory region of several genes. Required for neurogenesis in imaginal disks. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Required for transcription of Sim. Also functions independently of Notch pathway, in the development of the bristle sensory organ precursor cell ().

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Product Notes

The Su(H) su(h) (Catalog #AAA1303226) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-102, Full length protein. The amino acid sequence is listed below: NPNGSPLDPH QQQQQQQSQD MPHFGLPGPQ PPSSQQQQQQ MQVHHQQQQQ QQQQQQHQQQ MQMSLLPGPY RPHIEEKKLT RDAMEKYMRE RNDMVIVILH AK. It is sometimes possible for the material contained within the vial of "Protein suppressor of hairless (Su (H)), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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