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Western Blot (WB) (Western blot analysis of Syntaxin 1A phosphorylation expression in Mouse braintissue lysates, The lane on the left is treated with the antigen-specific peptide.)

Syntaxin 1A Antibody | anti-STX1 antibody

Phospho-Syntaxin 1A (Ser14) Antibody

Gene Names
STX1A; STX1; HPC-1; P35-1; SYN1A
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence, Immunocytochemistry
Purity
Immunogen affinity purified
Synonyms
Syntaxin 1A; Phospho-Syntaxin 1A (Ser14) Antibody; Neuron-specific antigen HPC-1; P35A; SAP; Synaptotagmin associated 35 kDa protein; syntaxin 1A; anti-STX1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
Phospho-Syntaxin 1A (Ser14) Antibody detects endogenous levels of Syntaxin 1A only when phosphorylated at Serine 14
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
251
Applicable Applications for anti-STX1 antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes
WB: 1:500-1:2000
IF/ICC: 1:100-1:500
Immunogen
A synthesized peptide derived from human Syntaxin 1A around the phosphorylation site of Serine 14
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of Syntaxin 1A phosphorylation expression in Mouse braintissue lysates, The lane on the left is treated with the antigen-specific peptide.)

Western Blot (WB) (Western blot analysis of Syntaxin 1A phosphorylation expression in Mouse braintissue lysates, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-STX1 antibody
STX1A is a type IV membrane protein involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. Three splice variant isoforms have been described.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35kDa
NCBI Official Full Name
syntaxin-1A isoform 2
NCBI Official Synonym Full Names
syntaxin 1A
NCBI Official Symbol
STX1A
NCBI Official Synonym Symbols
STX1; HPC-1; P35-1; SYN1A
NCBI Protein Information
syntaxin-1A
UniProt Protein Name
Syntaxin-1A
UniProt Gene Name
STX1A
UniProt Synonym Gene Names
STX1

NCBI Description

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Uniprot Description

Plays a role in hormone and neurotransmitter exocytosis (). Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm.

Research Articles on STX1

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Product Notes

The STX1 stx1a (Catalog #AAA8511644) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Phospho-Syntaxin 1A (Ser14) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Syntaxin 1A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC). WB: 1:500-1:2000 IF/ICC: 1:100-1:500. Researchers should empirically determine the suitability of the STX1 stx1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Syntaxin 1A, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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