Bovine STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) ELISA Kit | STT3A elisa kit
Bovine Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A, STT3A ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A
Catalytic activity: Dolichyl diphosphooligosaccharide + [protein]-L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine.
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Product Notes
The Bovine STT3A stt3a (Catalog #AAA9320451) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9320451 ELISA Kit recognizes Bovine STT3A. It is sometimes possible for the material contained within the vial of "STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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