Signal Transducer And Activator Of Transcription 2 (STAT2) Recombinant Protein | STAT2 recombinant protein

Recombinant Signal Transducer And Activator Of Transcription 2 (STAT2)

Cat. Num. AAA2018760

• Gene Names: Stat2; AW496480; 1600010G07Rik
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Signal Transducer And Activator Of Transcription 2 (STAT2); Recombinant Signal Transducer And Activator Of Transcription 2 (STAT2); STAT2 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- NPL RFLYPRIPRD EAFGCYYQEK VNLEEQEEYL KHKLIVISNR QVDELQQPLE LKQDSESLEV NAELLLAHDQ ELPLMMQTGL VLGTELKVDP ILSTAPQVLL EPAPQVLLEP APQVLLEPAP QVLLEPAPQV LLEPAPQVLL EPAPQVLLEP APQVQLEPAP QVLLELAPQV LLEPAPQVLL ELAPQVQLEP AHLLQQPSES DLPEDLQQIS VEDLKKLSNP STEYITTNEN PMLAGESSGD ETSIPYHSHF DA
• Sequence Length: 923

• Applicable Applications for STAT2 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Mus musculus (Mouse)
• Expression System: Prokaryotic expression
• Residues: Asn658~Ala912 (Accession # Q9WVL2) with two N-terminal Tags, His-tag and T7-tag
• Subcellular Location: Cytoplasm. Nucleus
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Predicted Isoelectric Point: 4.5
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 13633965
• NCBI GeneID: 20847
• UniProt Accession #: Q9WVL2; Q64188; Q64189; Q64250
• Molecular Weight: 32.2kDa
• NCBI Official Full Name: Signal transducer and activator of transcription 2
• NCBI Official Synonym Full Names: signal transducer and activator of transcription 2
• NCBI Official Symbol: Stat2
• NCBI Official Synonym Symbols: AW496480; 1600010G07Rik
• NCBI Protein Information: signal transducer and activator of transcription 2
• UniProt Protein Name: Signal transducer and activator of transcription 2
• Protein Family: Signal transducer and activator of transcription
• UniProt Gene Name: Stat2
• UniProt Entry Name: STAT2_MOUSE

Uniprot Description

STAT2: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Binds to the IFN-stimulated response element (ISRE) and to the Gas element. This multiprotein transcription factor is termed ISGF3. Two alternatively spliced isoforms have been described.

Protein type: DNA-binding; Transcription factor

Cellular Component: cytoplasm; plasma membrane; nucleus

Molecular Function: identical protein binding; protein binding; signal transducer activity; DNA binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; signal transduction