CMP-N-acetylneuraminate-poly-alpha-2, 8-sialyltransferase Recombinant Protein | SIA8D recombinant protein
Recombinant Human CMP-N-acetylneuraminate-poly-alpha-2, 8-sialyltransferase
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
ST8SIA4: Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. Belongs to the glycosyltransferase 29 family.
Protein type: EC 2.4.99.-; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Membrane protein, integral; Transferase
Chromosomal Location of Human Ortholog: 5q21.1
Cellular Component: Golgi membrane
Molecular Function: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialic acid binding
Biological Process: ganglioside biosynthetic process; N-glycan processing; nervous system development; oligosaccharide metabolic process; protein amino acid glycosylation; protein modification process
Research Articles on SIA8D
Similar Products
Product Notes
The SIA8D st8sia4 (Catalog #AAA9421267) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length of isoform 2 Lumenal, 21-168aa. The Recombinant Human CMP-N-acetylneuraminate-poly-alpha-2, 8-sialyltransferase reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "CMP-N-acetylneuraminate-poly-alpha-2, 8-sialyltransferase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
