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Small t antigen Recombinant Protein | HpVgp3 recombinant protein

Recombinant Hamster polyomavirus Small t antigen

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Small t antigen; Recombinant Hamster polyomavirus Small t antigen; HpVgp3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-194, Full length protein
Sequence
MDRILTKEEKQALISLLDLEPQYWGDYGRMQKCYKKKCLQLHPDKGGNEELMQQLNTLWTKLKDGLYRVRLLLGPSQVRRLGKDQWNLSLQQTFSGTYFRRLCRLPITCLRNKGISTCNCILCLLRKQHFLLKKSWRVPCLVLGECYCIDCFALWFGLPVTNMLVPLYAQFLAPIPVDWLDLNVHEVYNPASGP
Sequence Length
194
Species
Hamster polyomavirus (HaPyV)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,562 Da
NCBI Official Full Name
small T antigen
NCBI Official Symbol
HpVgp3
NCBI Protein Information
small T antigen
UniProt Protein Name
Small t antigen
Protein Family
UniProt Gene Name
ST
UniProt Synonym Gene Names
ST-AG

Uniprot Description

Promotes efficient viral genome replication by accelerating both G1 and S phase progression of the cell cycle. Inhibits host PP2A by binding to the A subunit, thereby displacing lower affinity regulatory B subunit. Inactivation of PP2A in turn results in the transactivation of cyclin A and cyclin D1 promoters. Late during the infection cycle, ST may induce dephosphorylation of host MTOR, leading to the inhibition of cap-dependent translation. May establish and maintain high levels of viral genomes during persistent infection in cell culture.

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Product Notes

The HpVgp3 st (Catalog #AAA1171660) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-194, Full length protein. The amino acid sequence is listed below: MDRILTKEEK QALISLLDLE PQYWGDYGRM QKCYKKKCLQ LHPDKGGNEE LMQQLNTLWT KLKDGLYRVR LLLGPSQVRR LGKDQWNLSL QQTFSGTYFR RLCRLPITCL RNKGISTCNC ILCLLRKQHF LLKKSWRVPC LVLGECYCID CFALWFGLPV TNMLVPLYAQ FLAPIPVDWL DLNVHEVYNP ASGP. It is sometimes possible for the material contained within the vial of "Small t antigen, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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