Western Blot (WB)
(GDI1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the GDI1 antibody detected the GDI1 protein (arrow).)
Rabbit anti-Human GDI1 Polyclonal Antibody | anti-GDI1 antibody
GDI1, CT (GDI1, GDIL, OPHN2, RABGDIA, XAP4, Rab GDP dissociation inhibitor alpha, Guanosine diphosphate dissociation inhibitor 1, Oligophrenin-2, Protein XAP-4)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(GDI1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the GDI1 antibody detected the GDI1 protein (arrow).)
Western Blot (WB)
(GDI1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the GDI1 antibody detected the GDI1 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Subunit structure: Interacts with RHOH. Interacts with RAB10; negatively regulates RAB10 association with membranes and activation. Ref.16 Ref.17
Subcellular location: Cytoplasm
By similarity.
Tissue specificity: Brain; predominant in neural and sensory tissues. Ref.15
Involvement in disease: Mental retardation, X-linked 41 (MRX41) [MIM:300849]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.19 Ref.20
Sequence similarities: Belongs to the Rab GDI family.
Research Articles on GDI1
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Product Notes
The GDI1 gdi1 (Catalog #AAA645579) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GDI1, CT (GDI1, GDIL, OPHN2, RABGDIA, XAP4, Rab GDP dissociation inhibitor alpha, Guanosine diphosphate dissociation inhibitor 1, Oligophrenin-2, Protein XAP-4) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GDI1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the GDI1 gdi1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GDI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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