TFIIH basal transcription factor complex p47 subunit (tfh47) Recombinant Protein | tfh47 recombinant protein
Recombinant Schizosaccharomyces pombe TFIIH basal transcription factor complex p47 subunit (tfh47)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
TFIIH basal transcription factor complex p47 subunit (tfh47); Recombinant Schizosaccharomyces pombe TFIIH basal transcription factor complex p47 subunit (tfh47); tfh47 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-421, Full length
Sequence
MNENQKSFDSDKSESEDEQKNGRVKVRSRKTDDNEGYTWEGEYQRSWDIVQEDAEGSLVGVIAGLIQSGKRKRLLRDTTPLQRGIIRHMVLVLDLSNSMEERDFHHKRFDLQIKYASEFVLEFFEQNPISQLSIIGVMDGIAHRITDLHGNPQSHIQKLKSLRDCSGNFSLQNALEMARASLSHIASHGTREVLIIFGSILSSDPGDIFKTIDALVHDSIRVRIVGLAAEVAICKEICNKTNSSTKNAYGVVISEQHFRELLLESTIPPATDSAKTTDASLVMMGFPSKVVEQLPSLCACHSIPSRGGFHCPRCKAKVCTLPIECPSCSLVLILSTHLARSYHHLFPLKNWSEIPWSANPKSTHCFACQLPFPKPPVSPFDESTSSMRYACPSCKNHFCLDCDVFAHEQLHECYGCQCSGN
Sequence Length
421
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,067 Da
NCBI Official Full Name
transcription factor TFIIH complex subunit Ssl1
NCBI Official Symbol
ssl1
NCBI Protein Information
transcription factor TFIIH complex subunit Ssl1
UniProt Protein Name
General transcription and DNA repair factor IIH subunit ssl1
Protein Family
UniProt Gene Name
ssl1
UniProt Synonym Gene Names
tfh47; TFIIH subunit ssl1; TFB subunit ssl1; SSL1 homolog
Uniprot Description
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
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Product Notes
The tfh47 ssl1 (Catalog #AAA1164670) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-421, Full length. The amino acid sequence is listed below: MNENQKSFDS DKSESEDEQK NGRVKVRSRK TDDNEGYTWE GEYQRSWDIV QEDAEGSLVG VIAGLIQSGK RKRLLRDTTP LQRGIIRHMV LVLDLSNSME ERDFHHKRFD LQIKYASEFV LEFFEQNPIS QLSIIGVMDG IAHRITDLHG NPQSHIQKLK SLRDCSGNFS LQNALEMARA SLSHIASHGT REVLIIFGSI LSSDPGDIFK TIDALVHDSI RVRIVGLAAE VAICKEICNK TNSSTKNAYG VVISEQHFRE LLLESTIPPA TDSAKTTDAS LVMMGFPSKV VEQLPSLCAC HSIPSRGGFH CPRCKAKVCT LPIECPSCSL VLILSTHLAR SYHHLFPLKN WSEIPWSANP KSTHCFACQL PFPKPPVSPF DESTSSMRYA CPSCKNHFCL DCDVFAHEQL HECYGCQCSG N. It is sometimes possible for the material contained within the vial of "TFIIH basal transcription factor complex p47 subunit (tfh47), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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