Typical Testing Data/Standard Curve (for reference only)
Mouse Sterol regulatory element-binding protein 2 ELISA Kit | Srebf2 elisa kit
Mouse Sterol regulatory element-binding protein 2 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
SREBP-2: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway. Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes. Belongs to the SREBP family.
Protein type: DNA-binding; Membrane protein, multi-pass; Transcription factor; Membrane protein, integral
Cellular Component: cytoplasm; cytoplasmic vesicle; dendrite; endoplasmic reticulum; Golgi apparatus; integral to membrane; intracellular membrane-bound organelle; membrane; nucleus
Molecular Function: chromatin binding; DNA binding; protein binding; protein C-terminus binding; protein dimerization activity; sequence-specific DNA binding; transcription factor activity
Biological Process: cellular response to starvation; cholesterol metabolic process; lipid metabolic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; response to hormone stimulus; steroid metabolic process; transcription, DNA-dependent
Research Articles on Srebf2
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Product Notes
The Mouse Srebf2 srebf2 (Catalog #AAA288965) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA288965 ELISA Kit recognizes Mouse Srebf2. It is sometimes possible for the material contained within the vial of "Sterol regulatory element-binding protein 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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