Western Blot (WB)
(Western Blot analysis of A549 cells using SRPX2 Monoclonal Antibody at dilution of 1:1000)
Mouse anti-Human, Mouse SRPX2 Monoclonal Antibody | anti-SRPX2 antibody
SRPX2 Monoclonal Antibody
Gene Names
SRPX2; BPP; CBPS; PMGX; RESDX; SRPUL
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
Protein A purification
Synonyms
SRPX2; Monoclonal Antibody; SRPX2 Monoclonal Antibody; BPP; CBPS; PMGX; RESDX; SRPUL; SRPX 2; Sushi repeat containing protein SRPX2; Sushi repeat containing protein X linked 2; Sushi repeat protein; Sushi repeat-containing protein SRPX2; anti-SRPX2 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
657
Purity/Purification
Protein A purification
Concentration
1mg/mL (varies by lot)
Sequence Length
465
Applicable Applications for anti-SRPX2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500-1:5000
IHC: 1:50-1:500
IF: 1:50-1:500
IHC: 1:50-1:500
IF: 1:50-1:500
Immunogen
Fusion protein of SRPX2
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of A549 cells using SRPX2 Monoclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of A549 cells using SRPX2 Monoclonal Antibody at dilution of 1:1000)
Related Product Information for anti-SRPX2 antibody
SRPX2 (sushi-repeat-containing protein, X-linked 2) is a secreted protein expressed in neurons of the human adult brain, including the rolandic area. Firstly described as sushi-repeat protein up-regulated in leukemia (SPRUL) in leukemia cells with dysregulated expression at the transcriptional level, SRPX2 has been recently shown as a multifunctional protein. SRPX2 is a ligand for uPAR, the urokinase-type plasminogen activator (uPA) receptor. It is involved in seizure disorders, angiogenesis and cellular adhesion. The involvement of SRPX2 in disorders of language cortex and cognition suggests it has an important role in the perisylvian region critical for language and cognitive development.
Product Categories/Family for anti-SRPX2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 53kDa
Observed: 53kDa
Observed: 53kDa
NCBI Official Full Name
sushi repeat-containing protein SRPX2
NCBI Official Synonym Full Names
sushi repeat containing protein X-linked 2
NCBI Official Symbol
SRPX2
NCBI Official Synonym Symbols
BPP; CBPS; PMGX; RESDX; SRPUL
NCBI Protein Information
sushi repeat-containing protein SRPX2
UniProt Protein Name
Sushi repeat-containing protein SRPX2
Protein Family
UniProt Gene Name
SRPX2
UniProt Synonym Gene Names
SRPUL
NCBI Description
This gene encodes a secreted protein that contains three sushi repeat motifs. The encoded protein may play a role in the development of speech and language centers in the brain. This protein may also be involved in angiogenesis. Mutations in this gene are the cause of bilateral perisylvian polymicrogyria, rolandic epilepsy, speech dyspraxia and cognitive disability. [provided by RefSeq, May 2010]
Uniprot Description
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development.
Research Articles on SRPX2
Similar Products
Product Notes
The SRPX2 srpx2 (Catalog #AAA2542076) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SRPX2 Monoclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SRPX2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500-1:5000 IHC: 1:50-1:500 IF: 1:50-1:500. Researchers should empirically determine the suitability of the SRPX2 srpx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRPX2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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