sRANK Recombinant Protein
sRANK, Human, Recombinant (Receptor for sRANKL, soluble RANK Ligand, Receptor Activator of NFkB Ligand)
Purity
Highly Purified
Synonyms
sRANK; Human; Recombinant (Receptor for sRANKL; soluble RANK Ligand; Receptor Activator of NFkB Ligand); sRANK recombinant protein
Host
E Coli
Purity/Purification
Highly Purified
Form/Format
Sterile ltered solution lyophilized from 10mM sodium phosphate, pH 7.2.
Biological Activity: Determined by its ability to suppress the production of IFN-gamma from human PBMC (peripheral blood mononuclear cells)s.
Biological Activity: Determined by its ability to suppress the production of IFN-gamma from human PBMC (peripheral blood mononuclear cells)s.
Sequence
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
Endotoxin Level
0.1ng/ug (1EU/ug).
Reconstitution
We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 degree C for 1 week or -20 degree C for future use.
Preparation and Storage
-20 degree C
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 degree C. Reconstituted sRANK should be stored in working aliquots at -20 degree C.
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 degree C. Reconstituted sRANK should be stored in working aliquots at -20 degree C.
Related Product Information for sRANK recombinant protein
RANKR, a member of the TNFR superfamily, is a type I transmembrane protein. RANK and RANKL have shown to be important regulators of the interactions between T-cells and dendritic cells. RANK is essential for RANKL-mediated osteoclastogenesis. In the presence of M-CSF in bone marrow cultures, RANKL stimulates osteoclastogensis and activation of mature osteoclasts to resorb bone by binding to RANKR. Human RANK is a soluble 19.3kDa protein containing 175 amino acid residues, comprising of the full-length of the TNF receptor-like extracellular domain of RANK Receptor.
Product Categories/Family for sRANK recombinant protein
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Product Notes
The sRANK (Catalog #AAA650217) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK. It is sometimes possible for the material contained within the vial of "sRANK, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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