Testican-1 Recombinant Protein | SPOCK1 recombinant protein

Human CellExp Testican-1; human recombinant

Cat. Num. AAA847071

• Gene Names: SPOCK1; TIC1; SPOCK; TESTICAN
• Applications: SDS-Page
• Purity: > 85%
• Synonyms: Testican-1; Human CellExp Testican-1; human recombinant; SPOCK; TIC1; TICN1; SPOCK1 recombinant protein

• Host: HEK 293 cells; Source: Human
• Purity/Purification: > 85%
• Form/Format: Lyophilized from 0.22 mum filtered solution in PBS; pH 7.4. Normally Trehalose is added as protectant before lyophilization.
• Sequence Length: 439

• Applicable Applications for SPOCK1 recombinant protein: SDS-PAGE
• Endotoxin Level: < 1.0 EU per/mug
• Reconstitution: Reconstitute in sterile deionized water to the desired protein concentration.
• Preparation and Storage: Store at -20 degree C for 12 months.; Centrifuge the vial prior to opening.

Testing Data

Related Product Information for SPOCK1 recombinant protein

Testican-1 is also known as protein SPOCK; SPOCK1; which contains one azal-like domain and one thyroglobulin type-1 domain. SPOCK1 is an extracellular heparan/chondroitin sulfate proteoglycan. Members of this family are known as testicans; also called SPOCKs. SPOCKs are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. They contain inhibitory regions in several domains targeted to different classes of protease; and in some cases may act as protease inhibitors. Little is known about SPOCK1's function until now. It may play a role in cell-cell and cell-matrix interactions except for contributing to various neuronal mechanisms in the central nervous system.

NCBI and Uniprot Product Information

• NCBI GI #: 4759164
• NCBI GeneID: 6695
• NCBI Accession #: NP_004589.1
• NCBI GenBank Nucleotide #: NM_004598.3
• UniProt Accession #: Q08629; Q59EW0; Q8N630; Q9UCL8; B3KSW3
• Molecular Weight: 47.8 kDa
• NCBI Official Full Name: testican-1
• NCBI Official Synonym Full Names: SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1
• NCBI Official Symbol: SPOCK1
• NCBI Official Synonym Symbols: TIC1; SPOCK; TESTICAN
• NCBI Protein Information: testican-1
• UniProt Protein Name: Testican-1
• Protein Family: Testican
• UniProt Gene Name: SPOCK1
• UniProt Synonym Gene Names: SPOCK; TIC1; TICN1

NCBI Description

This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008]

Uniprot Description

SPOCK1: May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system.

Protein type: Cell adhesion; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5q31.2

Cellular Component: cytoplasm; extracellular space; neuromuscular junction; sarcoplasm

Molecular Function: calcium ion binding; cysteine protease inhibitor activity; metalloendopeptidase inhibitor activity

Biological Process: central nervous system neuron differentiation; neurogenesis; neuron migration