Sheep Pulmonary Surfactant Associated Protein C ELISA Kit | SPC elisa kit

Sheep Pulmonary Surfactant Associated Protein C ELISA Kit

Cat. Num. AAA40491

• Gene Names: Sftpc; SP5; SPC; SP-C; Sftp2; Bricd6; Sftp-2; pro-SpC
• Reactivity: Sheep
• Synonyms: Pulmonary Surfactant Associated Protein C; Sheep Pulmonary Surfactant Associated Protein C ELISA Kit; SPC elisa kit

• Reactivity: Sheep
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Assay Type: Quantitative Sandwich
• Detection Range: 3.12 pg/ml - 100 pg/ml
• Sensitivity: 1.0 pg/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for SPC elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of SPC (hereafter termed "analyte") in undiluted original Sheep body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 256355065
• NCBI GeneID: 20389
• NCBI Accession #: NP_035489.2
• NCBI GenBank Nucleotide #: NM_011359.2
• UniProt Accession #: P21841
• Molecular Weight: 21,055 Da
• NCBI Official Full Name: pulmonary surfactant-associated protein C
• NCBI Official Synonym Full Names: surfactant associated protein C
• NCBI Official Symbol: Sftpc
• NCBI Official Synonym Symbols: SP5; SPC; SP-C; Sftp2; Bricd6; Sftp-2; pro-SpC
• NCBI Protein Information: pulmonary surfactant-associated protein C; pulmonary surfactant-associated proteolipid SPL(Val)
• UniProt Protein Name: Pulmonary surfactant-associated protein C
• UniProt Gene Name: Sftpc
• UniProt Synonym Gene Names: Sftp2; SP-C
• UniProt Entry Name: PSPC_MOUSE

Uniprot Description

SFTPC: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. Defects in SFTPC are the cause of pulmonary surfactant metabolism dysfunction type 2 (SMDP2); also called pulmonary alveolar proteinosis due to surfactant protein C deficiency. A rare disease associated with progressive respiratory insufficiency and lung disease with a variable clinical course, due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Genetic variations in SFTPC are a cause of susceptibility to respiratory distress syndrome in premature infants (RDS); also known as RDS in prematurity. RDS is a lung disease affecting usually premature newborn infants. It is characterized by deficient gas exchange, diffuse atelectasis, high-permeability lung edema and fibrin-rich alveolar deposits called 'hyaline membranes'. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Cellular Component: multivesicular body; extracellular space; cytoplasm; extracellular region

Molecular Function: protein homodimerization activity

Biological Process: protein homooligomerization