ACAT2 recombinant protein

Recombinant Human ACAT2 protein, N-His Tag

Cat. Num. AAA1560674

• Gene Names: SOAT2; ACAT2; ARGP2; ACACT2
• Purity: >90% as determined by SDS-PAGE
• Synonyms: ACAT2; Recombinant Human ACAT2 protein; N-His Tag; ACACT2; SOAT2; ACAT2 recombinant protein

• Host: E Coli
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized. Lyophilized from PBS pH 7.4, 0.2% NLS, 5% Trehalose, 5% Mannose, 1mM EDTA.

• Tag: N-His Tag
• Species: Homo sapiens (Human)
• Protein Construction: A DNA sequence encoding the human SOAT2 (Met1-Val397) was fused with the N-terminal His Tag
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Preparation and Storage: Store at 2 to 8 degree C for one week. Store at -20 to -80 degree C for twelve months from the date of receipt. Use a manual defrost freezer and avoid repeated freeze thaw cycles.; In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Product Categories/Family for ACAT2 recombinant protein

Protein

NCBI and Uniprot Product Information

• NCBI GI #: 68563320
• NCBI GeneID: 8435
• UniProt Accession #: O75908; Q4VB99; Q4VBA1; Q96TD4; Q9UNR2; F5H7W4; I6L9H9
• Molecular Weight: 57,614 Da
• NCBI Official Full Name: SOAT2 protein
• NCBI Official Synonym Full Names: sterol O-acyltransferase 2
• NCBI Official Symbol: SOAT2
• NCBI Official Synonym Symbols: ACAT2; ARGP2; ACACT2
• NCBI Protein Information: sterol O-acyltransferase 2
• UniProt Protein Name: Sterol O-acyltransferase 2
• Protein Family: Acetyl-CoA acetyltransferase
• UniProt Gene Name: SOAT2
• UniProt Synonym Gene Names: ACACT2; ACAT2; ACAT-2

NCBI Description

Summary:This gene is a member of a small family of acyl coenzyme A:cholesterol acyltransferases. The gene encodes a membrane-bound enzyme localized in the endoplasmic reticulum that produces intracellular cholesterol esters from long-chain fatty acyl CoA and cholesterol. The cholesterol esters are then stored as cytoplasmic lipid droplets inside the cell. The enzyme is implicated in cholesterol absorption in the intestine and in the assembly and secretion of apolipoprotein B-containing lipoproteins such as very low density lipoprotein (VLDL). Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.