snRNA-activating protein complex subunit 4 (SNAPC4) Recombinant Protein | SNAPC4 recombinant protein

Recombinant Human snRNA-activating protein complex subunit 4 (SNAPC4) , partial

• Gene Names: SNAPC4; SNAP190; PTFalpha
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: snRNA-activating protein complex subunit 4 (SNAPC4); Recombinant Human snRNA-activating protein complex subunit 4 (SNAPC4); partial; SNAPC4 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,469

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 92859678
• NCBI GeneID: 6621
• NCBI Accession #: NP_003077.2
• NCBI GenBank Nucleotide #: NM_003086.3
• UniProt Accession #: Q5SXM2; Q9Y6P7
• Molecular Weight: 159,433 Da
• NCBI Official Full Name: snRNA-activating protein complex subunit 4
• NCBI Official Synonym Full Names: small nuclear RNA activating complex polypeptide 4
• NCBI Official Symbol: SNAPC4
• NCBI Official Synonym Symbols: SNAP190; PTFalpha
• NCBI Protein Information: snRNA-activating protein complex subunit 4
• UniProt Protein Name: snRNA-activating protein complex subunit 4
• Protein Family: snRNA-activating protein complex
• UniProt Gene Name: SNAPC4
• UniProt Synonym Gene Names: SNAPc subunit 4; PSE-binding factor subunit alpha; PTF subunit alpha; SNAPc 190 kDa subunit

NCBI Description

This gene encodes the largest subunit of the small nuclear RNA-activating protein (SNAP) complex. The encoded protein contains a Myb DNA-binding domain, and is essential for RNA polymerase II and III polymerase transcription from small nuclear RNA promoters. A mutation in this gene is associated with ankylosing spondylitis. [provided by RefSeq, Jul 2016]

Uniprot Description

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.